Eravacycline
by Kayzelle Anne Castillo
1. Dosage and Dosage forms
1.1. For injection: 50 mg of eravacycline
2. Adverse reaction
2.1. nausea
2.2. vomiting
3. Warnings and Precaution
3.1. Hypersensitivity reactions
3.2. Tooth discoloration and Enamel hypoplasia
3.3. Inhibition of bone growth
3.4. Clostridium difficile-associated diarrhea
4. MOA
4.1. Protein 30S ribosomal subunit inhibitors
5. Chemical modifications
5.1. C-7
5.2. C-9
6. Tetraphase Pharmaceuticals
6.1. Xerava
6.2. FDA Approval
6.3. TP-434
6.4. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline
7. Drug compatibilities
7.1. 0.9% Sodium Chloride Injection, USP.
8. Class
8.1. Antibacterial drug
8.1.1. Tetracycline
8.1.1.1. Indication
8.1.1.1.1. Intra-abdominal infection
8.1.1.1.2. 18 years of age and older
8.1.1.2. Limitation of use
8.1.1.2.1. complicated urinary tract infections