vibrio cholera

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vibrio cholera by Mind Map: vibrio cholera

1. AB type- toxin(L.17)

2. known to have antibiotic efflux mechanism (L.22)

3. enterotoxin(L.17)

4. pathogen (lecture 17) with numerous virulence factors, including toxins (L. 17).

5. virulence factor(L.17)

6. .250 mg/kg LD50(L.17)

7. symptoms of disease: diarrhea which is due to AB toxin which binds and causes massive cAMP to be produced, preventing na+ from entering, massive cl- efflux, followed by massive water efflux and dehydration(L.17)

8. John Snow concluded cholera was spreading through water sources in Soho district of London (L.17)

9. bacterium, gram negative (L.17)

10. have restriction modification enzymes to regulate foreign DNA from a phage attack, have been observed, as well as phage gene transfer(L.19)

11. pilus is a virulence factor (L.17)

12. Cholera phages have shown to have CRISPR mechanism (L.20)

13. Emerging diversity of the CRISPR-Cas system in cholera phages | Atlas of Science

14. Phage-bacterial interactions in the evolution of toxigenic Vibrio cholerae

15. adaptive immunity (T cells and B cells) may help in warding off infection (L 20)

16. artificial passive immunity to help with toxin, much like the diphtheria toxin used (L21)

17. transmitted through contaminated water, food, fecal mater, etc (L.22)

18. tetracycline is a commonly prescribed antibiotic to fight this infection (L.22). It is listed as a broad spectrum antibiotic.

19. Antibiotic resistance mechanisms of Vibrio cholerae. - PubMed - NCBI