Monoamine Oxidase Inhibitor

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Monoamine Oxidase Inhibitor by Mind Map: Monoamine Oxidase Inhibitor

1. Side Effects

1.1. Risk of triggering hypertensive crisis if patient eats foods that are rich in Tyramine (such as avocado's, cheese and alcohol).

1.1.1. Treatment for Hypertensive crisis: Sodium Nitropusside, Phentolamine, Labetalol

1.2. Orthostatic hypotension

1.3. CNS stimulation

2. Used for: treat Atypical Depression.

2.1. As effective as TCA's & SSNRI's but less toxic

3. Selegiline (Emsam)

3.1. Lower risk of hypertensive crisis with trans dermal route compared to oral

3.2. First transdermal treatment for depression.

3.3. Enters system without going through GI tract

4. Used to: Increase the levels of noephrinepine, serotonin, and dopamine by blocking monoamine oxidase.

5. Second or third choice of Antidepressants