MTHFR Related Health Problems

This map describes health conditions related to MTHFR genetic anomalies in the methylation pathway.

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MTHFR Related Health Problems by Mind Map: MTHFR Related Health Problems

1. Definition

1.1. Methyl TetraHydro Folate Reductase Deficiency

1.2. Results in Slower than Nomal Methylation Processes

1.3. Wiki

1.4. Heterozygous

1.4.1. Only one Gene

1.4.1.1. Function 50 to 70%

1.4.1.2. 40% of Population

1.5. Homozygous

1.5.1. Both Genes Affected

1.5.1.1. 30% of Normal Function

1.5.1.2. 10% of Population

2. Types

2.1. 50 Variations

2.2. Most Common

2.2.1. 677

2.2.1.1. Affects Folate Metabolism

2.2.2. 1298

2.2.3. 677 +1298

2.2.3.1. Compound Heterozygous

3. Attributes

3.1. 677

3.1.1. Elevated Homocysteine

3.1.2. Cardio Vascular Disease

3.1.3. Stroke

3.1.4. DVT (Deep Venous Thrombosus)

3.1.5. Peripheral Neuropathy

3.1.6. Still Births

3.1.7. Pre-Eclampsia, Neural Tube, Cleft Lip

3.2. 1298

3.2.1. Depression, Anxiety, IBS

3.2.2. Fibromyalgia

3.2.3. Chronic Fatigue

3.2.4. Dementia

3.2.5. Schizophrenia

3.2.6. Parkinson's

3.2.7. TetraHydroBiopterin Problems (BH4)

3.2.8. Migraines

3.3. 677 + 1298

3.3.1. Symptoms of Both Defects

3.3.2. More Severe

3.3.3. Blood Clots

3.4. All have Problems

3.4.1. Clearing Heavy Metals

3.4.1.1. Lead

3.4.1.2. Mercury

3.4.1.3. Aluminum

3.4.2. Symptoms Progress with Time

3.4.3. Cancer Risk Increased

3.4.4. Renal Failure

3.4.5. Addiction Potential

3.4.5.1. Drugs

3.4.5.2. Video Games

3.4.5.3. Pornography

3.5. Aggravating Factors

3.5.1. Heavy Metal Exposure

3.5.1.1. Amalgams

3.5.1.2. Vaccines

3.5.1.3. Fish

3.5.1.4. Aluminum Cookware

3.5.1.5. Occupational

3.5.2. Poor Diet

3.5.2.1. Processed Foods

3.5.2.2. Hydrogenated Fats

3.5.3. Anesthesia

3.5.3.1. Especially Nitrous Oxide

3.5.4. Other Enzyme Defects

3.5.5. Comorbid Disease

3.5.5.1. Diabetes

3.5.5.2. Lymphoma

3.5.5.3. Leiden Factor V

3.6. Helpful Measures

3.6.1. Dietary

3.6.1.1. Vegetables

3.6.1.2. Berries

3.6.1.3. Fruits

3.6.2. Exercise

3.6.3. Music

4. Treatment

4.1. Supplements

4.1.1. MB12

4.1.1.1. Sub Lingual MB12

4.1.1.2. Compounded

4.1.1.3. Inj. Every 3 Days

4.1.2. Methyl Folate

4.1.2.1. L-methyl folate

4.1.3. Methyl donors

4.1.3.1. DMG

4.1.3.2. TMG (Betaine)

4.1.3.3. Methyl Matrix

4.1.4. Fatty Acids

4.1.4.1. Fish Oils

4.1.4.1.1. Good tasting

4.1.4.2. Flax Seed

4.1.5. Minerals

4.1.5.1. Zinc

4.1.5.1.1. 20 -40mg/day

4.1.5.2. Selenium

4.1.5.3. Magnesium

4.1.5.4. Trace Minerals

4.1.5.4.1. Methylation Minerals

4.1.6. Vitamins

4.1.6.1. Vit E

4.1.6.2. Vit C

4.1.6.3. Amino Acids

4.1.6.4. B Complex

4.1.7. Herbs

4.1.7.1. Silymarin

4.1.7.1.1. Liver Detoxifier

4.1.8. MTHFR Specialty

4.1.8.1. Methyl Matrix

4.1.8.2. Protocols MB12 + Folate

4.2. Medications

4.2.1. Active Forms of Folate

4.2.1.1. MetaNx

4.2.1.2. Neevo

4.2.1.3. Deplin

4.2.1.4. Cerefolin

5. Diet

5.1. Avoid

5.1.1. Hydrogenated Fats

5.1.2. Processed Foods

5.2. Increase

5.2.1. Vegetables

5.2.2. Fruits

6. Toxin Control

6.1. Avoid

6.1.1. Household Chemicals

6.1.1.1. Artificial Scents

6.1.1.2. Cleansers

6.1.1.3. Pesticides

6.1.2. Chronic Chemical Exposures

7. Detoxification

7.1. Nutritional Plan

7.2. Body Cleansers

7.2.1. InfraRed Sauna

7.2.2. Clay Baths

7.3. Rules

7.3.1. Fix Bowel 1st

7.3.2. Do Slowly

8. Lab Testing

8.1. Blood

8.1.1. Common Labs

8.1.1.1. Liver Enzymes

8.1.1.2. Ferritin

8.1.1.3. Homocysteine

8.1.1.4. HS Crp

8.1.2. Nitro Tyrosine

8.1.2.1. Measures Oxidative Stress

8.1.2.2. Special Lab only

8.1.3. Glutathione

8.1.4. B12

8.1.4.1. May be High

8.1.4.2. Body Unable to Use

8.1.5. Genetic

8.1.5.1. Standard Labs

8.1.5.1.1. Much More Expense

8.1.5.1.2. Less Data

8.1.5.1.3. Labs

8.2. Saliva

8.2.1. Genetic

8.2.1.1. 23anme profile

8.2.1.2. Need software to interrupt

8.2.1.2.1. Livewello

8.2.1.2.2. Promethease

8.3. Urine

8.3.1. Heavy Metal Challenge

8.3.2. Urine Organic Acids

8.3.3. Toxin Screen

8.4. Misc

8.4.1. GI Health

8.4.1.1. If GI Symptoms Present

8.4.2. Food Allergy

9. By Stephen Smith MD, NWImed.com/MTHFR

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