1. Symptoms
1.1. Hyperthyroidism
1.1.1. Disruptions in Cognition, Concentration and Clarity of Thoughts
1.1.2. Mood Lability, Emotional Dysregulation, Irritability, Anxiety, Agitation
1.1.3. Cardiac Palpitations, Arrhythmias, Cardiomegaly and subsequent failure,
1.1.4. Muscle wasting from protein metabolism
1.1.5. Infertility
1.1.6. Heat Intolerance
1.1.7. Lowered TSH, elevated T3 and T4
1.1.8. Weight Loss and increased appetite
1.1.9. Very high energy level
1.2. Hypothyroidism
1.2.1. Elevated TSH, decreased T3 and T4
1.2.2. Disruptions in Cognition, Cloudy Thinking, Poor Concentration
1.2.3. Cold Intolerance
1.2.4. Bradycardia, faint cardiac impulses
1.2.5. Hypokinesia with generalized muscle weakness.
1.2.6. Periorbital edema/ankle edema
1.2.7. Diminished libido
1.2.8. Weight gain and decreased appetite
1.2.9. Very low energy level
2. Epidemiology
2.1. Sex
2.1.1. More common in female
2.2. Age
2.2.1. 20-40 year old
2.2.2. Elderly
2.3. Biological
2.3.1. Autoimmune
2.3.1.1. Graves disease
2.3.2. Dysfunctional Pituitary or Hypothalamus
2.4. Lifestyle
2.4.1. pregnancy
2.4.2. third world country
2.4.2.1. lacks dietary iodine
2.4.3. consumption of animal thyroid/hormones
2.5. Congenital
2.5.1. aplasia/hypoplasia of thyroid
2.6. Medications
2.6.1. Lithium
2.6.2. Amiodarone
2.6.3. Iodine
3. Diagnosis
3.1. Thyroid scan
3.1.1. Radioactive Iodine uptake
3.2. Testing Hormone Levels
3.2.1. Thyroid stimulating hormone
3.2.1.1. TSH elevated in hypo
3.2.1.2. TSH suppressed in hyper
3.2.2. Free and Total Thyroxine T3
3.2.3. Thyrotropin Releasing Testing
3.3. Testing for detectable antibodies
3.3.1. Thyroidal Peroxidase
3.3.2. Thyroglobulin antibody
3.3.3. TSH Receptor antibody
4. Treatment
4.1. Anti-thyroid drug therapy
4.2. Synthetic hormone therapy
4.2.1. Levothyroxine
4.3. Carcinoma/Tumor
4.3.1. Radiation
4.3.2. Chemotherapy
4.3.3. Surgery