Crohn's Disease

1. Pathophysiology

1.1. formation of granulomatous lesions.

1.2. lesions are surrounded by normal mucosal tissue.

1.3. Inflamed bowel usually take ‘’ cobblestone ‘’ appearance

1.4. The bowel wall becomes thickened and inflexible.

2. Risk factors

2.1. Age

2.2. Ethnicity

2.3. Family history

2.4. Cigarette smoking

2.5. Nonsteroidal anti-inflammatory medications

3. Clinical manifistaion

3.1. Diarrhea

3.2. fever

3.3. Blood in your poop

3.4. Lack of appetite

3.5. Belly pain and cramps

3.6. Urgent bowel movements

3.7. Lack of appetite

4. Etiology

4.1. Autoimmune disorded

4.2. Heredity

4.3. environmental factor