Lymphoma

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Lymphoma by Mind Map: Lymphoma

1. malignant neoplasm of lypmphocytes

2. MOST COMMON primary malignancy that occurs in the head and neck region 2nd to SCC

3. Location & extent of Dx affects staging Tx & prognosis

4. presents with enlarged, painless mobile lymph nodes of the neck

5. Most common head/neck region for extranodal lymphoma in Waldeyer's ring:

5.1. tonsils

5.2. nasopharyns

5.3. base of tongue region

6. other sites:

6.1. paranasal sinus

6.2. nasal cavity

6.3. larynx

6.4. oral cavity

6.5. parotid gland

6.6. thyroid

7. Work-up:

7.1. FNA

7.2. open biopsy if FNA tissue is insufficinet

8. Staging Work-up:

8.1. Labs

8.2. CXR to r/o mediastinal involvement

8.3. CT head/neck w/&w/o contrast

8.4. MRI chest/abd/pelvis

8.5. Bone marrow biopsy

9. Hodgkin's

9.1. 15% of lymphomas

9.2. poss. origination in B-lymphocytes

9.3. Disease process of lymph nodes only

9.4. REED-STERNBERG cells are histopathological findings

9.5. Ave. onset=27y/o

10. Non-Hodgkin's

10.1. 85% of all lymphomas

10.2. Poss. origination of B & T lymphocytes

10.3. usually presents as disease process of extranodal & lymph nodes

10.4. Ave. onset=67y/o

11. Ann Arbor Staging Classification for both Hodgkin's & Non-Hodgkin's

11.1. Stage I: single lymph node region

11.2. Stage II: 2 or more regions

11.3. Stage III: both sides of diaphragm

11.4. Stage IV: diffuse

11.5. A-Absence of systemic symptoms

11.6. B-Presence of systemic symptoms

11.7. C-Localized extranodal extension

11.8. S-Splenic involvement