Osteogenesis Imperfecta

1. Causative Factors

2. Risk Factors

3. Diagnostic Screening

3.1. X-rays

3.2. DNA tests

3.3. Blood tests/Urine tests

3.4. Biochemical testing

3.5. Prenatal Testing

3.6. Genetic testing

3.7. DXA Bone Density Scan

4. Genetic Variations

4.1. COL1A1 Gene

4.2. COL1A2 Gene

4.3. CRTAO Gene

4.4. LEPRE1 Gene

5. Names

5.1. Brittle Bones

5.2. OI

5.3. Vrolik Disease

5.4. Fragilitas Ossuim

5.5. Lobstein Disease

5.6. Osteopsathyrosis

5.7. Porak

5.8. Durante Disease

6. Clinical Manifestions

6.1. Weak muscles

6.1.1. bone deformities

6.1.1.1. Hearing Loss

6.1.1.1.1. Fatigue

7. Treatment

7.1. Mild

7.2. Moderate

7.3. Severe

8. Pathology

9. Types

9.1. Type I

9.2. Type II

9.3. Type III

9.4. Type IV

9.5. Type V

9.6. Type VI