Muscle Relaxants

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Muscle Relaxants by Mind Map: Muscle Relaxants

1. II. Roles of Muscle Relaxants

1.1. Anti-Spasms (Anti-spasmodic)

1.1.1. Reducing Normal Tone (For Surgical & Respiratory Paralysis)

1.1.2. Treating Temporary Spasms Rest & S/T Relief of muscle spasms Often combined with NSAIDs or Acetaminophen (See Analgesics) Very Helpful for PT Procedural Interventions both acute, as well as chronic

1.1.3. Anti-spasticity / Anti-rigidity

1.1.4. Dual Use - Anti-temporary spasms & anti-spasticity

1.2. Drug Types by Site of Action

1.2.1. Centrally Acting Drugs Brain & Spinal Cord Acting Benzodiazepines Carisoprodol (Soma) Cyclobenzaprene (Flexeril) Spinal Neuron Acting Zanaflex Baclofen (Lioresal) Others (Mechanism or Exact Site of Action Unknown but believed to be CNS level action without action on Skeletal Muscle Methcarbamol (Robaxin) Metaxalone (Skelaxin) Chlorzoxazone (Paraflex) Orphenadrine (Norflex)

1.2.2. Skeletal Muscle Acting Spinal Cord Alpha Motor Neuron (LMN) Inhibitor Botulinum Toxin NMBA (Neuromuscular Blocking Agents) Non-depolarizing NMBAs Depolarizing NMBAs Direct Skeletal Muscle Inhibitor Dantrolene sodium

2. I. Tonal Abnormalities

2.1. 1. When Normal Tone is undesirable

2.2. 2. Spasms

2.2.1. Temporary

2.2.2. Permanent

3. III. Relevance to Physical Therapists

3.1. Acute Pain Scenarios

3.1.1. Facilitates therapy

3.2. Post-surgical & ICU Patient Management

3.2.1. Need for early intervention to prevent lasting weakness

3.3. Facilitates therapy in CNS Spasm Syndromes

3.3.1. Stretching,

3.3.2. ROM,

3.3.3. Skin crease hygeine

3.4. Prognostication of Need for Optimal Drug Delivery Mechanisms