WILMS TUMOUR

1. ABNORMALITY IN GENETIC IMPRINTING; CHROMOSOME 11 DISTAL TO WT1 LOCI

1.1. BECKWITH WIDDEMAN SYNDROME

1.1.1. ENLARGEMENT OF ORGANS LIKE MACROGLOSSIA

1.1.2. HEMIHYPERTROPHY

2. WT1 GENE(CHROMOSOME 11p13

2.1. WAGR

2.1.1. ANIRIDIA

2.1.2. RETARDATION MENTAL

2.1.3. GENITAL DYSGENESIS

2.2. DENYS -DRASH SYNDROME(DDS)

2.2.1. GONADAL DYSGENESIS

2.2.2. RENAL ABNORMALITIES