Thrombocytopenia

1. pseudothrombocytopenia

2. decreased platelet production

2.1. Viral infections

2.2. HIV

2.3. Chemotherapy

2.4. Aplastic anaemia

2.5. Alcohol

2.6. Megaloblastic anaemia

3. Increased platelet destruction

3.1. ITP

3.2. SLE

3.3. TTP

3.4. DIC

3.5. Alloimmune destruction (post transfusion)

3.6. HELLP

3.7. Drugs

3.7.1. Heparin

3.7.2. Quinine

3.7.3. Quinidine

3.7.4. Valproate

3.7.5. Ondansatron

3.7.6. Phenytoin

3.7.7. Septrin

3.8. physical destruction

3.8.1. CPB

3.8.2. mechanical valves

4. Dilutional

4.1. Blood loss and transfusion

5. Splenic sequestration