ANEMIA

1. Vit B12/ Folate

2. CBC

2.1. Low Hb/ Hct/ RBC count

2.2. RBC indices

2.3. Peripheral smear

2.4. Bone marrow

3. Clinical features

3.1. Hypoxia

3.1.1. Cerebral

3.1.2. Generalised

3.1.3. Myocardial

3.2. Low Hb

3.2.1. pale, glossitis, stomatitis

4. Laboratory features

4.1. Biochemistry

4.1.1. Iron profile

4.1.2. Bilirubin

4.2. Coomb's test, Hb electrophoresis

5. Definition

5.1. Low Hb/ RBC count+ Tissue hypoxia

6. Classification

6.1. Aetiological

6.1.1. Decreased production

6.1.1.1. Nutritional deficiency

6.1.1.2. Stem cell defect

6.1.1.3. Marrow infiltration

6.1.1.4. Anemia of chronic disease

6.1.2. Increased RBC loss

6.1.2.1. Acute blood loss

6.1.2.2. Hemolysis

6.2. Hypersplenism

6.3. Morphological

6.3.1. NCNC

6.3.1.1. Acute blood loss

6.3.2. MCHC

6.3.3. Macrocytic

6.3.3.1. Megaloblastic

6.3.3.2. IDA, Thalassemia