Pfizer-BioNTech Risk-Benefit Tree

1. Benefits

1.1. Decreased risk of COVID-19 Infection

1.1.1. 95% effective at preventing COVID-19 Infection

1.1.2. 100% effective at preventing severe COVID-19 illness

1.1.3. Increased chance of herd immunity

2. Risks

2.1. Reactogenicity Symptoms

2.1.1. Local

2.1.1.1. Vaccination Site Reactions

2.1.1.1.1. Vaccination site pain

2.1.1.1.2. Vaccination site pruritus

2.1.1.1.3. Vaccination site bruising

2.1.1.1.4. Vaccination site erythema

2.1.1.2. Lymphadenopathy

2.1.2. Systemic

2.1.2.1. Headache

2.1.2.2. Fevers/Chills

2.1.2.3. Fatigue

2.1.2.4. Arthralgia / Myalgia

2.2. Severe Allergic Reactions

2.2.1. Anaphylaxis

2.2.1.1. Generalized urticaria

2.2.1.2. Difficulty breathing

2.2.1.3. Swelling of lips

2.2.1.4. Swelling of airway

2.2.2. Non-Anaphylaxis

2.2.2.1. Pruritus

2.2.2.2. Diffuse rash

2.2.2.3. Mild respiratory symptoms

2.3. Cardiac Reactions

2.3.1. Myocarditis

2.3.2. Pericarditis