While I'm here - session 3

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While I'm here - session 3 by Mind Map: While I'm here - session 3

1. Step 9

1.1. Review session 2

1.2. mechanism flow chart

1.3. 20 minutes

2. Step 10

2.1. Management

2.1.1. staging & prognosis Rai staging system Stage 0 — 150 months Stage I — 101 months Stage II — 71 months Stages III and IV — 19 months Binet staging system Stage A — comparable to age-matched controls Stage B — 84 months Stage C — 24 months other factors male, del17, and early chemotherapy can worsen prognosis or doubling of cells in 1 year depends on age, stage and patient overall health

2.1.2. treatment indications weight loss more than 10 percent in 6 months, fatigue, night sweats, doubling of cells in less than 12 months, organomegaly

2.1.3. goals of treatment control symtoms, monitoring patient state, control complications and increase in overall survival

2.1.4. treatment options chemotherapy prophylaxis method is not beneficial indicated in stage 3 or 4 target replicating cells along with normal cell can be followed by radiation therapy in some cases fludarabine, cyclophosphamide and rituximab (FCR) tumor lysis syndrome can cause metabolic imbalance which can cause renal faliure (but its mainly in acute cases) nasuea and vomiting are common side effects clinical trials might be a good option for termianlly ill patients infections are common, so prophylaxis can be given (influenza and pnumococcal) start with corticoseroids in early stages in poor performane patient the aim is to control symptoms by less agressive chemo and in case of co-morbidity a single chemo agent can be given alemtuzumab monoclonal antibody that binds to cd52 thyat can be given with the FCR combination SCT curative not pallitive allogenic addition of alemtuzumab to prevent graft versus host disease radiotherapy can be used for organomegaly immunoglobulin can be given for hypogammaglobulinemia

2.2. 60 minutes

3. step 11

3.1. Review and evaluate

3.2. Group members

3.3. Chairman

3.4. Scribe

3.5. Tutor

3.6. Material

3.7. 10 minutes