Allergic Rhinitis, Cough, & Cold

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Allergic Rhinitis, Cough, & Cold 저자: Mind Map: Allergic Rhinitis, Cough, & Cold

1. Pediatric cough & cold, use caution...

1.1. Children < 18

1.1.1. Avoid codeine- & hydrocodone-containing products

1.2. Children < 4

1.2.1. Avoid OTC cough & cold products

1.3. Children < 2

1.3.1. Avoid OTC cough & could

1.3.2. Avoid promethazine

1.3.3. Avoid topical menthol & camphor

2. Intranasal steroids

2.1. :arrow_down: inflammation

2.2. Considered 1st line for moderate-severe symptoms

2.2.1. **Budesonide (Rhinocort)**

2.2.1.1. Preferred in **pregnancy**

2.2.2. **Fluticasone (Flonase)**

2.2.3. **Triamcinolone (Nasocort)**

2.2.4. Beclamethasone (Beconase, QNasl)

2.2.4.1. Preferred in **pregnancy**

3. Antihistamines

3.1. 1st Gen

3.1.1. Diphenhydramine, chlorpheniramine, doxylamine (Unisom SleepTabs)

3.2. 2nd Gen

3.2.1. Cetirizine

3.2.1.1. Preferred in **pregnancy** along w/ Loratadine

3.2.2. Levocetirizine (Xyzal)

3.2.2.1. C/I in ESRD, hemodialysis

3.2.3. Fexofenadine (Allegra)

3.2.3.1. Take w/ water & avoid coadministration w/ aluminum/mg-containing products

3.3. Intranasal

3.3.1. Azelastine (Astepro)

3.3.1.1. Can be combined w/ intranasal steroid

4. Decongestants

4.1. Alpha-adrenergic agonists (sympathomimetics)

4.1.1. Max sudafed purchase per day: 3.6g; per 30 days: 9g

4.1.2. Phenylephrine nasal spray (neo-synephrine)

4.2. Cause vasoconstriction which :arrow_down: sinus vessel engorgement

5. Misc. allergy meds

5.1. **Intranasal cromolyn (NasalCrom)**

5.1.1. OTC Mast cell stabilizer

5.1.2. Safe in pregnancy

6. Cough suppressants

6.1. DM

6.1.1. Suppress cough reflex in medullary cough center

6.1.2. At high-doses, acts as NMDA blocker leading to euphoria & hallucinations similar to PCP

6.2. Codeine

6.2.1. Suppress at medullary

6.3. Benzonatate

6.3.1. Topical anesthetic on respiratory stretch receptors