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TEDxAmsterdam 2013 StemBell by Mind Map: TEDxAmsterdam 2013
5.0 stars - 2 reviews range from 0 to 5

TEDxAmsterdam 2013 StemBell

We're now able to create a world where people don't suffer from heart attacks anymore


we need to futher develop our technique, making it available to patients, we need to do this in clinical trials, really expensive

we need someone to help us bring this idea to patients, we don't want tthis beautiful solutiion to be put on the shelf

we need one brave pioneer

to help getting the product into the patients


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...the author

Benno Naaijkens, Interview at TEDxAmsterdam, TEDxAmsterdam Award 2013 Winner, VU University Medical Center

...this talk

Themes, Stem cells

Related talks, Hans Clevers - Stem cells: Dr Jekyll or Mr Hyde?

Reactions, Here all details on 'Dynamics of #StemBells in an ultrasound field', winner of the @TEDxAms Award 2013 => … #StemBell, “@TEDxAms: #TEDxAmsterdam Award 2013: The Winner Is… StemBell #TEDxAms ” Let's make this real! Crowd sourcing???

view this talk on YouTube

Imagine a world...

... where people suffering from a heart attack actually get better

... these patients no longer die years after their infarction

The challenge: Myocardial infarction

what is it? what happens?

occlusion of an coronary artery, see Wikipedia article

a part of the heart dies

scar tissue is formed, because the heart cannot regenerate itself

the heart doesn't function as well anymore as it did before, scar tissue is very rigid


heart failure, one of he most devastating diseases in the world, affecting at least 100.000.000 people world wide

Developed new solution: StemBells


Stem cells

microbubbles and ultrasound

how does it work?

attaching stem cells to microbubbles, see this actual image of a stembell

target them specifically to the right place in the heart, pushing them via ultrasound


increase the number of cells in damaged tissue

results from a recent study

injecting stembells into rats, resulting in an 8-fold increase in the number of cells specifically in the right place in the heart

does this lead to a better functioning heart?, yes!, 70% reduction of the damaged area

possbile existing solutions

usage of stem cells?

stem cells can be any cells, so: also heart cells

unfortunately, injecting these stem cells into patients didn't work, not enough stem cells reached and attached to the damaged areas of the heart

tried another solution: microbubbles and ultrasound

what is it?, smal gass-filled bubbles that you van delivery to any part of the body that you want