Testicular CA

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Testicular CA by Mind Map: Testicular CA

1. Primary Neoplasms

1.1. Germ Cell Tumors

1.1.1. Seminomas

1.1.1.1. Classic Seminomas

1.1.1.1.1. MARKERS

1.1.1.1.2. HISTOLOGY

1.1.1.1.3. AGE 40-50 y/o

1.1.1.1.4. Most common malignant testicular tumor

1.1.1.2. Spermatocytic Seminomas

1.1.1.2.1. HISTOLOGY

1.1.1.2.2. AGE > 65 y/o

1.1.2. Non-Seminomas

1.1.2.1. Embryonal Carcinoma

1.1.2.1.1. MARKERS

1.1.2.1.2. DERIVATIVE

1.1.2.1.3. HISTOLOGY

1.1.2.1.4. AGE 20-30 y/o

1.1.2.1.5. More aggressive than seminomas

1.1.2.2. Teratomas

1.1.2.2.1. Immature Teratomas

1.1.2.2.2. Mature Teratomas

1.1.2.2.3. Malignant Transformations

1.1.2.2.4. DERIVATIVE

1.1.2.2.5. ANY AGE

1.1.2.3. Choriocarcinoma

1.1.2.3.1. MARKERS

1.1.2.3.2. DERIVATIVE

1.1.2.3.3. HISTOLOGY

1.1.2.4. Yolk Sac Tumor

1.1.2.4.1. MARKERS

1.1.2.4.2. DERIVATIVE

1.1.2.4.3. HISTOLOGY

1.1.2.4.4. CHILDREN < 3 y/o

1.2. Sex Cord Stromal Tumors

1.2.1. Leydig Cell Tumors

1.2.1.1. HISTOLOGY

1.2.1.1.1. Leydig Cells- Reinke crystals

1.2.1.2. PRESENTS WITH

1.2.1.2.1. Endocrine Sx

1.2.2. Sertoli Cell Tumors

1.2.2.1. HISTOLOGY

1.2.2.1.1. Cords resembling seminiferous tubules

1.2.2.2. PRESENTS WITH

1.2.2.2.1. Estrogen Sx

1.2.2.2.2. Gynecomastia and Impotence

1.2.3. MARKERS

1.2.3.1. Inhibin

2. Secondary Neoplasms

2.1. Testicular Lymphoma

2.1.1. HISTOLOGY

2.1.1.1. CD20+ B Cells

2.1.2. AGE >65 y/o

3. Precursor Neoplasms

3.1. Intratubular Germ Cell Neoplasia (ITGCN)