1. Biofilm Definition
1.1. Bacterial Colonies Living Within a Self Constructed Structured Environment
2. Structure
2.1. Collection of microbial communities
2.1.1. Encased in a Matrix of Extracellular Polymeric Substances
2.1.2. Made of
2.1.2.1. Negatively Charged Polysaccharides
2.1.2.2. Positively Charged Metal ions
2.1.2.3. Polysaccharides Vary by Bacteria
3. Properties
3.1. Multiple Channels
3.2. Diffusion of Nutrients & Genetic Materials
3.3. Protective Functions
3.4. Resistant to Anti-Biotics and Microbials
3.4.1. 100 to 1000 Fold More Resistant
3.5. Communication
3.5.1. Quorum Sensing
3.5.2. Chemicals
3.5.2.1. Gram -
3.5.2.1.1. Lactones
3.5.2.2. E-Coli
3.5.2.2.1. Epinephrine
3.5.2.3. Gram +
3.5.2.3.1. Cyclic Peptides
4. Chelating Agents
4.1. Iron chelators
4.1.1. Transferrin
4.1.2. Lactoferrin
4.1.2.1. P aeruginosa
4.2. EDTA
4.2.1. Binds on Cat ions Holding Matrix Together
4.2.2. Staph
4.2.2.1. EDTA
4.2.2.2. Vancomycin
4.2.3. Blocked by Ca or Fe
4.3. Frequently Combined with Enzymes
4.3.1. SIBO Ease Plus
5. SIBO
5.1. Overgrowth of Bacteria in Small Bowel
5.1.1. >100,000 CFU/ml
5.2. Dysbiosis
5.2.1. Presence of Pathogenic Bacteria
5.2.2. Found in Biofilms
5.2.3. Symptoms
5.2.3.1. persistent/Recurrent Dysbiosis
5.2.3.2. Recurrent Sinusitis
5.2.3.3. Initially do well on Antibiotic or Antifungals
5.2.3.4. Frequent Flaring of Yeast/Bacterial During Detox
5.2.3.5. Associated with Autoimmune Disease
6. More Information
7. Author
7.1. Stephen Smith MD | NWImed.com | Agapenutrition.com | Protocolsforhealth.com
7.1.1. AgapeNutriton
7.1.2. ProtocolsforHealth.com
7.1.3. Nwimed.com
7.1.4. AutisminaNutshell.com
7.1.5. Subscribe to our Newsletter
8. 3 Steps
8.1. Treatment Sequencing
8.1.1. 3 Steps
8.1.1.1. 1. Enzymes and Chelators
8.1.1.2. 2. Killing Agents
8.1.1.3. 3. Clean-up
8.2. Biofilm Dysrupters
8.2.1. Proteolytic Enzymes
8.2.1.1. Products
8.2.1.1.1. SIBO Ease Plus
8.2.1.1.2. SIBO Ease
8.2.1.2. Dissolve Matrix
8.2.2. Probiotics and Prebiotics
8.2.3. Given on Empty Stomach
8.3. Killing Agents
8.3.1. Antibiotics
8.3.1.1. Rifaximin
8.3.1.1.1. Xifaxan
8.3.2. Natural Compounds
8.3.2.1. Herbal
8.3.2.1.1. olive leaf
8.3.2.1.2. grape seed extract
8.3.2.1.3. oregano
8.3.2.1.4. Wormwood
8.3.2.1.5. Artemesia
8.3.2.1.6. Combination
8.3.2.2. Probiotics
8.3.2.2.1. Secrete Antibacterial Substances
8.3.2.3. Gensium Violet
8.4. Clean up
8.4.1. Agents
8.4.1.1. Fiber
8.4.1.2. Activated Charcoal
8.4.1.3. Alginates, Brown Algae
8.4.1.4. Modified Citrus Pectin
8.4.1.5. GI Detox
8.4.2. Given Away from Meds & Supplements
8.4.2.1. Bind Drugs and Supplements Making them Ineffective
8.4.3. Reduces Side Effects from Die-Off