Pharmacogenomics of drugs used to treat Covid-19- Group2

1. Types of drugs for treating Covid-19

2. Metabolic enzymes in metabolism of drugs used to treat Covid-19

3. potential adverse events due pharmacogenetics variants or drug-drug interactions

4. Genetic risk factor could increase the risk of suffering severe Covid-19

5. GWAS studies

6. remdesivir

7. SARS-CoV-2

8. SARS-CoV

9. angiotensin converting enzyme 2 (ACD2)

10. elevated aminotransferase and bilirubin levels

11. diarrhea, rash, renal impairment

12. hypotension

13. chloroquine and hydroxychloroquine diminish the effect of Remdesivir

13.1. CYP3A4 Inducers decrease the serum concentration of Remdesivir

14. genomewide association study

15. cross-replicating association study

16. MERS-CoV