THROMBOELASTOGRAM (TEG)

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THROMBOELASTOGRAM (TEG) by Mind Map: THROMBOELASTOGRAM (TEG)

1. Principle

1.1. Formation of Clots (Intrinsic &Extrinsic pathways)

1.1.1. Difficult to measure

1.1.2. Dynamic Process (Clot Formation isnt something that just happens)

1.2. Lab Tests

1.2.1. aptt

1.2.2. inr

1.2.3. Static

1.2.4. Data gives Speed and time of Clot forming- coagulation not Quality of CLot

2. Developed in 1948

2.1. Used Primarily in Liver Transplants

3. WHY TEG?

3.1. Measures Whole Process

3.1.1. Process of Clot Formation

3.1.2. Clot Dissolution (time clot likely to hold)

4. What Benefits?

4.1. Allows wider picture of Hemostatic function

4.1.1. begins with Interaction of Platelets and protein clot cascade.

4.1.2. From the time initial Platelet and fibrin interaction

4.1.3. Platelet Aggregation

4.1.4. Clot Strengthening

4.1.5. Fibrin Cross Linkage

4.1.6. to eventual clot lysis (clot distruction)

4.2. Gives the time

4.3. Rate the the Clot is Forming

4.4. Stability of Clot

4.5. Determines how well the Clot perform its function

4.5.1. Add enzyme called Heparin eze(enzyme) to machine will give you a trace of how the blood would be like. So you can do sample before too, and be able to see the difference

5. WHY?

5.1. Reduces Transfusions

5.2. There are Shortages of Blood

5.3. Limitations of Tests- Offers complete testing of haemostasis.

5.4. Designed to test the Dynamics of the Blood and Genetics (Coagulation) of the Blood

6. ADVANTAGES

6.1. Monitors HAEMOSTASIS As A WHOLE DYNAMIC PROCESS NOT just a Static Process

6.2. NOT Isolated like Conventional Tests.

7. MEASURES

7.1. ViscoElastic Properties of Blood

7.2. HOW ?