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Neuro immunology M. Schwartz, Israel by Mind Map: Neuro immunology M. Schwartz, Israel
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Neuro immunology M. Schwartz, Israel

Be careful: Immune cells actived in the brain / spinal cord, does not mean good/bad!

Diversity of phenotype of immune cells

Immune cells support neuronal survival!

Macrophage heterogeneity and tissue lipids

Huge confusion on what anti-inflammatory reactions are good or bad(!)

What is the role of the blood-borne monocytes

Interim summary

Naive monocytes are numerous in the blood, why their recruitment to the CNS is limited

proposed: a chronic disease may be dormant long before onset, due to an equilibrium between the cns risk factors and the immune system; onset and progression means loss of equilibrium - insufficient immunity or immune dysfunction

in ALS or AD we would suggest: anti-inflammatory should be the LAST drugs to use!!

Meeting notes by

Paul de Roos

Mindmap hosted on

Meeting