1. COMPONENTS
1.1. Cardiovascular system
1.1.1. heart
2. lymphatic system
2.1. primary organ
2.1.1. bone marrow, thymus
2.2. secondary organ
2.2.1. adenoid, spleen, tonsils, lymph nodes, MALT
3. mononuclear phagocytic system
3.1. macrophages and reticular fibres
4. cardiovascular
4.1. heart and thymus
5. CELLS
6. Leukocytes
6.1. basophiles
6.1.1. inflammation
6.1.1.1. release histamine
6.2. neutrophils
6.2.1. bacterial infection
6.2.1.1. fever
6.3. eosinophils
6.3.1. parasitic infection
6.3.1.1. allergic reaction
6.4. monocytes
6.4.1. become macrophages
6.4.1.1. phagocytic activity
6.5. lymphocytes
6.5.1. t cell and B cell
6.6. mast cell
6.6.1. release granules
6.7. natural killer cell (NKC)
7. 1st LINE DEFENCES
8. external physical barrier
8.1. saliva
8.2. tears
8.3. mucus lining
8.4. skin
8.5. genetica
8.6. stomach acis
8.7. gut bacteria
9. 2nd LINE DIFENCES
10. internal physiological barrier
10.1. fever
10.1.1. initiated by pyrogenes
10.1.1.1. increased body temperature
10.2. inflammation
10.2.1. redness
10.2.1.1. heat
10.2.1.1.1. pain
10.2.2. tissue cut
10.2.2.1. dilation
10.2.2.1.1. release cytokines
10.3. phagocytosis
10.3.1. phagosome fuse with lysosome
10.3.1.1. phagolysosome
10.3.2. attachment
10.3.2.1. ingestion
10.3.2.1.1. killing
10.4. antiomicrobial protein
10.4.1. complement system
10.4.1.1. cascade reaction
10.4.2. interferons
10.4.2.1. 3 major type
10.4.2.1.1. IFN-alpha
10.4.2.1.2. IFN-beta
10.4.2.1.3. IFN-gamma
10.4.3. iron binding protein
10.4.3.1. hemoglobin
10.4.3.2. lactoferrin
10.4.3.3. transferrin
10.4.4. antimicrobial peptide
10.4.4.1. bacteriosins
10.4.4.2. defensins
10.4.4.3. magainins
10.4.4.4. protegrins