Cholesterol Lowering Drugs
von Nicholas Fields
1. Cholesterol absorption inhibitors
2. Fibric acid derivatives
3. Statins
3.1. Decrease the hepatic synthesis of cholesterol. Inhibit enzyme HMG CoA reductase
3.2. Inhibition of enzyme also causes up-regulation of hepatic LDL receptors allowing the liver to remove more cholesterol from blood causing a decrease in LDL cholesterol.
4. Bile acid sequestrants
5. Nicotinic acid