1.1. MOA: inhibit Na and K transport across cell membranes; increase intracellular Ca; positive inotrope; PSNS effects
1.2. for ctrl'ing vent response in afib; HF; narrow TI so monitor drug levels periodically
1.3. AE: arrhythmias; av blocks, sinus bradycardia and vent extrasystoles common; hypokalemia; hypomagnesemia; low K levels can dangerously affect dig toxicity; n/v anorexia; visual disturbances; reversal agen: digibind
1.4. CI: drug interactions: antibiotics reduce bioavailability; diuretics cause hypokalemia and increase digoxin toxicity; many antiarrhythmics increase digoxin toxicity
2. adenosine
2.1. MOA: binds to adenosine receptors and activates K currents in atria, SA and AV nodes -> hyperpolarization and decreased conduction
