3.1. Symptoms include Increased or decreased need for sleep.
3.2. Appearing unusually energetic, or overly fatigued.
3.3. Increased or decreased appetite.
3.4. Various physical symptoms such as nausea, headache, or dizziness.
3.5. Drug is taken to prevent withdrawal symptoms.
3.6. Tolerance.
4. Chronic disease
4.1. Drug addiction is a chronic disease characterized by compulsive, or uncontrollable, drug seeking and use despite harmful consequences and changes in the brain, which can be long lasting. These changes in the brain can lead to the harmful behaviors seen in people who use drugs.
5. Heroin
5.1. "downer effect"
5.2. Signs during or shortly after use thats noticable includes Shortness of breath
5.3. Dry mouth
5.4. Constricted (small) pupils
5.5. Sudden changes in behavior or actions
5.6. Disorientation
5.7. Cycles of hyper alertness followed by suddenly nodding off
5.8. Droopy appearance, as if extremities are heavy
6. Methamphetamine
6.1. Symptoms include increased attention and decreased fatigue.