1. Decreased Production
1.1. Nutricional
1.1.1. B12 deficiency
1.1.2. Folate Deficiency
1.1.3. Copper
1.2. Bone Marrow Damage
1.2.1. Aplastic Anemia
1.2.2. Chemotherapy, Radiation
1.2.3. Drug-Induce
1.2.3.1. thiazides
1.2.3.2. antibiotics
1.2.4. Malignancy
1.2.4.1. Mieloma
1.2.4.2. Lymphona
1.2.4.3. Leukemia
1.2.4.4. Solid Tumor Metastases
1.2.4.5. Mielodysplasia
1.2.5. Mielofibrosis?
1.3. Congenital
1.3.1. Fanconis Anemia
1.3.2. Alborts
1.3.3. Granulomatous Disease
2. Others
2.1. Dilutional
2.1.1. Massive Transfusion
2.1.2. Fluid Resusitation
2.2. Pseudothobocytopenia
2.2.1. Platelet Clumping
3. Increased Consumption
3.1. Non - Inmune Mediated
3.1.1. MAHA: Microangiopatic
3.1.1.1. DIC
3.1.1.2. TTP
3.1.1.3. HUS
3.1.1.4. Preeclampsia/HELLP
3.1.1.5. Malignant Hypertention
3.1.2. Macroangiopatic
3.1.2.1. Valvular disease
3.2. Inmune Mediated
3.2.1. Primary ITP
3.2.2. Secindary ITP
3.2.2.1. Infection
3.2.2.1.1. VIH
3.2.2.1.2. HCV
3.2.2.1.3. EBV
3.2.2.2. SLE
3.2.2.3. Antiphospholipid antibody syndrome?
3.2.2.4. CLL, Lymphona
3.2.2.5. Drug Induce
3.2.2.5.1. Heparine HIT
3.2.2.5.2. antibiotics
3.2.2.5.3. antiepileptics