Lipoproteins

1. Major groups of Lipoproteins

1.1. Triacylglycerol

1.1.1. chylomicrons

1.1.1.1. apo-B-48

1.1.1.2. apo-A

1.1.1.3. apo C

1.1.1.4. apo E

1.1.2. VLDL

1.1.2.1. apo_B-100

1.1.2.2. apo CI

1.1.2.3. apoCII

1.1.2.4. apoCIII

1.2. cholesterol

1.2.1. LDL

1.2.1.1. apoB100

1.2.1.2. associated with Atherosclerosis

1.2.1.2.1. pathogenesis

1.2.1.2.2. risk factors

1.2.2. HDL

1.2.2.1. apo AI

1.2.2.2. apoC

1.2.2.3. apoD

1.2.2.4. apoE

2. Major Lipid Classes found

2.1. ampiphatic

2.1.1. cholesterol

2.1.1.1. syntesis

2.1.1.1.1. SYNTHESIS of Mevalonate

2.1.1.1.2. Formation of Isoprenoid Units

2.1.1.1.3. Condensation of Isoprenoids

2.1.1.1.4. Cyclization of squalene to form lanosterol

2.1.1.1.5. Formation of cholesterol

2.1.1.2. regulation

2.1.1.2.1. SERBP

2.1.1.2.2. INsIG

2.1.2. phospholipid

2.2. Non-polar

2.2.1. triacylglycerides

2.2.2. cholesteryl esters