cell injury: aging

pathophysiology

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cell injury: aging by Mind Map: cell injury: aging

1. normal

1.1. inevitable

1.1.1. THEORY 1

1.2. universal

1.3. accumulation

1.3.1. damaged macromolecules

1.3.1.1. Accumulate

1.3.1.1.1. THEORY 2

2. lifespan

2.1. 80-100 years

2.2. current generation

2.2.1. maybe shorter

2.3. time from birth to death

2.4. life expectancy

2.4.1. years of life remaining

3. changes

3.1. degenerative

3.1.1. extracellular

3.2. cellular

3.3. tissue

3.4. systemic

3.5. frailty

3.5.1. apoptosis

3.5.2. oxidative stress

3.5.3. physical inactivity

3.5.4. hormone disregulation

3.5.5. malnutrition

3.6. reduced physiologic reserve

3.7. increased care needs