The Immune System

Nursing - The Immune System

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The Immune System by Mind Map: The Immune System

1. Leukocytes

1.1. Lymphocytes

1.1.1. T Cells Regulatory T Cells Hepler T Cells Suppressor T Cells Effector T Cells Cytotoxic T Cells T cells mature in the thymus Cell-Mediated Response

1.1.2. B Cells Plasma Cells Produce Antibodies Humoral Response! Memory Cells They "remember" antigens and convert into a plasma cell when the antigen is detected B cells mature in the bone marrow

1.2. Neutrophils

1.2.1. Microphage Small cells within the blood that migrate tissue after a cell-mediated response Performs phagocytosis

1.3. Monocytes

1.3.1. Macrophage Large cells in tissues & organs Performs phagocytosis

2. Lymphoid Tissues

2.1. Lymphatic System

2.1.1. Tonsils & Adenoids Filters bacteria from oral and nasal passages

2.1.2. Spleen Reservoir of blood, removes bacteria & old red blood cells

2.1.3. Lymph Nodes Contains both B and T cells Removes bacteria and other particles from the lymph system

2.1.4. Thymus Gland Produces lymphocytes during fetal development After birth, this gland "programs" T cells

2.1.5. Bone marrow

2.2. Diagnostics

2.2.1. Lymph node biopsy

2.2.2. Ultrasound of the spleen

2.2.3. Lymphangiography

2.2.4. Radiography

2.2.5. CT

2.2.6. MRI

3. Natural Killer Cells

3.1. Cells that circulate through body looking for infected & cancerous cells

3.1.1. Once identified, NK cells release chemicals that causes cell death to the infected cell

4. Antibodies

4.1. Proteins that bind to antigens and promote destruction of cells

4.1.1. Neutralize toxins

4.1.2. Link antigens together causing agglutination

4.1.3. Cause them to precipitate and become solid

4.2. Immunoglobulins

4.2.1. IgG Most abundant immunoglobulin Location: Intravascular & intercellular fluid Neutralized bacterial toxins, accelerates phagocytosis IgG = Gestational = can be passed from mom to baby

4.2.2. IgE Least abundant antibody Location: Surface of basophils and mast cells Releases chemicals such as histamines and bradykinin Allergic, hypersensitivity, and inflammatory reactions

4.2.3. IgD Location: Lymphocyte surface Binds to antigens & promotes secretion of other immunoglobulins

4.2.4. IgM Location: Intravascular serum Agglutinates antigens and lyses cell walls

4.2.5. IgA Found in body secretions likes saliva, sweat, tears, mucus, bile, colostrum IgA = A = Airway! Also in GI tract Interferes with pathogens at exposed pathways

4.2.6. G.A.M.E.D.

5. Nonantibody Proteins

5.1. Complement System

5.1.1. Chain activation of proteins in response to an antibody binding to an antigen Proteins attack the cell membrane, which causes the destruction of the cell

5.2. Cytokines

5.2.1. Chemical Messengers released by lymphocytes, monocytes, macrophages Interleukins Chemical messenger between leukocytes and blood cell producing tissues Interferons Protect cells from viral invasion Slow viral replication Can be utilized for AIDS and some cancers Tumor Necrosis Factor Anti-tumor effects Helps with cellular repair in small amounts Utilized to regulate autoimmune and inflammatory disorders Colony-Stimulating Factors Prompt bone marrow to produce and mature blood cells epoetin alfa (Epogen), filgrastim (Neupogen), pegfilgrastim (Neulasta), sargramostim (Leukine)

6. Immune System: Innate and Adaptive Immunity Explained

6.1. Immune Crash Course #1

6.1.1. Immune Crash Course #2 Immune Crash Course #3

7. Types of Immunity

8. Nursing Care for the Immune System