DOLLY THE SHEEP
by Korina Škegro

1. ILLNESSES AND DEATH
1.1. 2000 - Jaagsiekte sheep retrovirus (JSRV)
1.2. 2001 - arthritis - successfully treated
1.3. 14th February 2003 - death (euthanasia) - tumours growing in lungs
2. DOLLY NOW
2.1. National Museum of Scotland - Edinburgh
3. DOLLY'S LIFE
3.1. announced: 22nd February 1997
3.1.1. public debate - benefits/dangers
3.2. shorter telomeres
3.2.1. DNA - more damage with aging
3.3. 6 children
3.3.1. first lamb - Bonnie
3.3.2. twins Sally and Rosie
3.3.2.1. -Welsh Mountain ram called David
3.3.3. triplets Lucy, Darcy and Cotton
4. MAKING DOLLY
4.1. The Roslin Institute
4.1.1. led by: Professor Sir Ian Wilmut
4.1.2. scientists, embryologists, surgeons, vets , farm staff
4.2. goal/idea
4.2.1. specialised cell -> a new animal?
4.2.2. a better method for producing genetically modified livestock
4.3. DNA came from mammary cell
4.4. born: 5th July 1996
4.4.1. surrogate mother: Scottish Blackface
4.5. white face - first sign of cloning
5. IMPORTANCE OF DOLLY
5.1. first mammal cloned from an adult cell
5.2. proof - cloning is possible
5.2.1. specialised cells -> exact copy of the animal
5.3. biology and medicine
5.3.1. personalised stem cells (iPS cells)