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Fetal Death by Mind Map: Fetal Death
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Fetal Death

Maternal Causes

demographic conditions

AMA

poverty

obesity

infections

parvovirus, listeria, CMV, toxo, syphilis

exposures/trauma

radiation, drugs (MTX)

medical conditions

immune, Rh isoimmunization

autoimmune, SLE, APA syndrome

hormonal, DM, Thyroid

CV/renovascular, Chr HTN, Pre-Eclampsia/Eclampsia, renal insufficiency

hematologic, thrombophilias

Fetal Causes

chromosomal

monosomies, 45X

trisomies, Tr16, Tr22, Tr21, Tr18, Tr13

polyploidy, triploidy

genetic

hemoglobinopathy, alpha-thalassemia

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congenital anomalies

infections

Definitions

developmental

embryonic (6-9wks) + pre-embryonic / anembryonic (2-5wks), majority of pregnancy losses (30% of all clinically recognized pregnancies)

fetal (10-40wks), minority of pregnancy losses (5% of all on-going pregnancies are lost after 10wks)

historical/clinical

abortions (< 20wks), late (>10wks), early (<10wks)

stillbirths (> 20wks), some states use >24wks, WHO Classification = >20wks or 500g

Obstetric Causes

Multiple Gestation

TTTS

Uterus

cervical insufficiency

uterine anomalies, septum

uterine rupture

Placenta

umbilical cord, "accident", vasa previa, velamentous insertion, prolapse, thrombosis

abnormal placentation, poor implantation, ectopic, dysmaturity/proloned pregnancy, abruption, fetomaternal hemorrhage, insufficiency

Epidemiology

~6/1000LB

stable rate over last 20 yrs

2x higher in AfrAm

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