The Future of Schizophrenia

1. History of the disease

1.1. Our info known about disease from clinical observations

1.2. emerges in late adolescent/early adulthood

1.2.1. heightened between 18-25 years old

1.2.2. has been seen earlier with patterns of delayed maturation in 1 year olds

1.3. still lack information on the disease, therefore can't find proper treatment

1.4. conflict in deciding what schizophrenia actually was & what it really effected within the body

1.4.1. dopamine disorder

1.4.2. fundamental disorder of thought & feeling

1.4.3. dementia praecox

2. What is it?

2.1. cronic mental disorder

2.2. 1% of the worlds pop. has it

2.3. Neurodevelopment disorder?

2.4. paranoid delusions and auditory hallucinations

2.5. many different perspectives on why it is caused/different hypothesis

3. Social impact

3.1. hard to find work in you have this disease (20% don't have jobs in Europe)

3.2. 20% of schizophrenics are homeless

3.3. many put into justice system instead of hospitals

4. Treatment?

4.1. many medications, none proven to fully reverse the disease

4.1.1. because causes are unclear

4.2. scientists found genetic and chromosomal ties

4.2.1. 43 genes found that could be linked to the disease

4.3. early detection & early intervention

4.3.1. cognitive focus and family support

4.4. somatic, psychosocial and cognitive treat- ments

5. pathophysiology of Schizophrenia

5.1. neurodevelopment approach, brain circuitry

5.2. forms as the prefrontal context is developing (18-25)

5.3. as circuits mature scientists try to find which circuits they formed from, which work together, which are hurtful in the process of helping schizophrenia

5.4. lower IQ in children going to develop the disease

5.5. prenatal treatment may have an impact

6. 4 Stages of Schizophrenia

6.1. 1. Risk (loot into genes see if there are abnormal connections)

6.2. 2. prodrome (before psychosis,looks for changes in behaviour and patterns, abnormal ones could give evidence of disease in future)

6.3. 3. psychosis manifested by delusions and hallucination (negative, core features of disease shown)

6.4. 4. ironic disability (unable to function properly,medical complications)