1. Definition
1.1. Methyl TetraHydro Folate Reductase Deficiency
1.2. Results in Slower than Nomal Methylation Processes
1.3. Wiki
2. Caveats
2.1. Go Slow
2.1.1. Pts Crash Easily
2.1.2. Change 1 Modality at a Time
2.1.3. Start with Low Dose and Titrate up
2.2. Fix the Gut 1st
2.2.1. Before Detoxification
2.2.2. Before Chelation
2.2.3. Constipation
2.2.3.1. Toxin Re Circulation
2.2.3.2. Releases GI Toxins into the System
2.3. If Problems Occur
2.3.1. GI Health Panel
2.3.1.1. Freq Findings
2.3.1.1.1. Gluten Enteropathy
2.3.1.1.2. Parasites
2.3.1.1.3. Infections
2.3.1.1.4. Yeast
2.3.2. CoMorb Conditions
2.3.2.1. Hormone Deficiency
2.3.2.2. Malnutrition
2.3.2.2.1. Amino Acids
2.3.2.2.2. Minerals
3. Treatment
3.1. Supplements
3.1.1. Methyl Donors
3.1.1.1. DMG
3.1.1.2. TMG (Betaine)
3.1.2. Fatty Acids
3.1.2.1. Fish Oils
3.1.2.2. Flax Seed
3.1.3. Minerals
3.1.3.1. Zinc
3.1.3.1.1. 20 -40mg/day
3.1.3.2. Selenium
3.1.3.3. Magnesium
3.1.4. Vitamins
3.1.4.1. Vit E
3.1.4.2. Vit C
3.1.4.3. Amino Acids
3.1.4.4. B Complex
3.1.5. Herbs
3.1.5.1. Silymarin
3.1.5.1.1. Liver detoxifier
3.2. Medications
3.2.1. Active Forms of Folate
3.2.1.1. MetaNx
3.2.1.2. Neevo
3.2.1.3. Deplin
3.2.1.4. Cerefolin
3.2.1.5. L methyl Folate
3.2.1.5.1. Hard to Find
3.2.1.6. Side Effects
3.2.1.6.1. May Cause Detox Reaction
3.2.1.6.2. Brain Fog Temporarily
3.2.1.6.3. Too Much
3.2.2. MB12
3.2.2.1. Not Well Absorbed Orally
3.2.2.2. Compounded
3.2.2.3. Inj. Every 3 Days
3.2.2.4. 2500 to 3,500mcg/Dose
3.2.2.5. Give in Buttock
3.2.2.5.1. Slows Release
3.2.2.5.2. SC Not IM
3.2.2.6. SL Form
3.2.2.6.1. Has Some Effect
4. Diet
4.1. Avoid
4.1.1. Hydrogenated Fats
4.1.2. Processed Foods
4.2. Increase
4.2.1. Vegetables
4.2.2. Fruits
5. Toxin Control
5.1. Avoid
5.1.1. Household chemicals
5.1.1.1. Artificial Scents
5.1.1.2. Cleansers
5.1.1.3. Pesticides
5.1.2. Chronic Chemical Exposures
5.2. Use
5.2.1. Safe Chemicals
5.2.1.1. Cleansers
5.2.1.2. Organic Pest Control
6. Detoxification
6.1. Nutritional Plan
6.2. Body Cleansers
6.2.1. InfraRed Sauna
6.2.2. Clay Baths
6.2.3. Colonics
6.3. Rules
6.3.1. Fix Bowel 1st
6.3.2. Do Slowly
6.3.3. Homeopathics Helpful
7. Lab Testing
7.1. Blood
7.1.1. Common Labs
7.1.1.1. Liver Enzymes
7.1.1.2. Ferritin
7.1.1.3. Homocysteine
7.1.1.4. HS Crp
7.1.2. Genetic
7.1.2.1. MTHFR Profile
7.1.3. Nitro Tyrosine
7.1.3.1. Measures Oxidative Stress
7.1.3.2. Special Lab Only
7.1.4. Glutathione
7.1.4.1. Usually Low
7.1.5. B12
7.1.5.1. May be High
7.1.5.2. Body Unable to Use
7.2. Urine
7.2.1. Heavy Metal Challenge
7.2.2. Urine Organic Acids
7.2.3. Toxin Screen
7.2.4. 2nd Tier
7.2.4.1. Amino Acids
7.2.4.2. Porphryns
7.3. Misc
7.3.1. GI Health
7.3.1.1. If GI symptoms present
7.3.1.2. Treatment Failure
7.3.2. Food Allergy