Carbon nano-tube in ophthalmic drug delivery

1. Methods and techniques for preparation

1.1. Electronic Arc method

1.2. Laser ablation method

1.3. Carbon vaporization deposition (CVD)

1.3.1. water assisted CVD

1.3.2. Oxygen assisted CVD

1.3.3. Radio frequency CVD

1.3.4. Catalyst assisted CVD

2. Applications for Ophthalmology

2.1. Delivery antibiotic , anti cholinergic drugs to retina as it's pass retinal -BBB

2.2. Enhance corneal matrix

2.3. Deiivery of the drugs to the cornea

3. Structure

3.1. single wall carbon nanotube

3.1.1. Characters of SW-CNT

3.1.1.1. Single layer

3.1.1.2. synthesis with catalyst

3.1.1.3. Low purity level

3.2. Multi wall carbon nanotube

3.2.1. Characters of MW-CNT

3.2.1.1. Multiple layer

3.2.1.2. Synthesis without catalyst

3.2.1.3. High purity level

4. Advantages

4.1. High thermal conductivity

4.2. High surface area

4.3. High mechanical strength

4.4. High efficiency to target organ

5. Disadvantage

5.1. Nondegredable

5.2. large surface area for protein opsonization

5.3. Required toxicology profile

5.4. bundling , large structure with less than opiumim biological behavoir