1. Anatomically human
1.1. Recent African Replacement
1.2. Multiregional Evolution
2. Investigation of human origins
2.1. Indirect Approach
2.1.1. patterns of genetic variation
2.2. Direct Approach
2.2.1. Recover DNA for extinct humans
3. Going Global by Adapting Local
3.1. Pressures
3.1.1. Migration and colonization
3.1.2. UV, Soil, Water, climate, and pathogens
3.1.2.1. Correlation between skin color and latitude
3.1.3. Concomitant changes
3.1.4. New mutations
3.1.5. Positive Selection
3.2. Centers of origin of agriculture
3.2.1. 9 homelands of agriculture
3.2.2. Food production confers advantage to farmers over hunters
3.2.3. Challenges in adapting to new diets
3.2.3.1. Lactose Persistence
4. How did become to be?
4.1. Pre-Darwin
4.1.1. Great apes
4.1.2. Humans
4.2. 1900's
4.2.1. Great Apes
4.2.1.1. Humans
4.3. 1960's
4.3.1. Asian Apes
4.3.1.1. African Apes
4.3.1.1.1. Humans
4.4. 1997
4.4.1. Neandertal Bones
4.5. 1987-2009
4.5.1. Standard Model of Human Origins
4.5.1.1. Population spread across Africa
4.5.1.2. Migrated out of Africa
4.5.1.3. Did not interbreed, but instead replaced
4.6. 2018
4.6.1. Genome of a Densisova-Neanderthal Hybrid