1. Colinergic drugs
1.1. Direct acting (receptor agonist)
1.1.1. Carbachol
1.1.1.1. Nicotinic, muscarini receptor
1.1.1.1.1. Solution
1.1.2. Alkaloids: pilocarpin
1.1.2.1. Muscarinic effect ,little nicotinic effect
1.1.2.1.1. Solution
1.1.3. Ester of choline: Bethanechol
1.1.3.1. Muscarinic activity
1.1.3.1.1. Oral , subcutaneous
1.1.4. Alkaloids from fungal
1.1.4.1. Amunate muscarinic
1.1.4.1.1. No uses clinical because highly toxic
1.1.5. Acetylcholine
1.1.5.1. Used to produce mlosis in ophthalmic surgery
1.2. Indirect acting ( cholinesterase inhibitors )
1.2.1. Physostigimine
1.2.1.1. Inhibit cholinesterase
1.2.1.1.1. Ophthalmi solution
1.2.2. Neostigimine
1.2.2.1. Inhibit of Acetylcholinesterase
1.2.2.1.1. Parenteral
1.2.3. Pyridostigmine
1.2.3.1. Inhibit of Acetylcholineesterase
1.2.3.1.1. Orally tablet
1.2.4. Edrophonium
1.2.4.1. Reversible inhibit of Acertylcholinesterase
1.2.4.1.1. Solution
1.2.5. Antidote
1.2.5.1. Sulfate injection
1.2.5.1.1. 1- Atropine may antagonize there effect large repeated dose Atropine
1.2.5.1.2. 2- pralidoxim: reactivate acetylcholine enzyme after inhibited by irreversible inhibition
2. Anticholinergic drugs
2.1. Atropine also called “Hyoscymie”
2.1.1. Parenterl IV or IM , eye drop
2.1.1.1. 1-usea of ophthalmology dilate pupil for refractive examination
2.1.1.2. 2- for enesthesia premedication to inhibit excessive salivary and bronchial secretion and to prevent
2.1.1.3. 3- used with anesthesia to prevent vagel mediated bradycardia
2.1.1.4. 4- Antidote for organophosphate poisoning or mushroom poison
2.1.1.5. 5- treatment of parkinsonism
2.1.1.6. 6- Antispasmodic and anti secretary for GI or GU hypermotility
2.2. Scopolamin “Hysocine” , Buscopan
2.2.1. Tablet ,IV,IM
2.2.1.1. 1- used motion sickness
2.2.1.2. 2- Dysmenorrhea
2.2.1.3. 3- preAnesthtic decrease secretion
2.2.1.4. 4- Antib-spasmodic
2.2.1.5. 5- ulcer
2.3. Homatropin “Allospasmin”
2.3.1. Eye drop, oral
2.3.1.1. 1- used for eye examination
2.3.1.2. 2- Anti-spasmodic
2.4. Ipratropium “Atrovent”
2.4.1. Inhalaties
2.4.1.1. Used for the treatment of chronic obstructive pulmonary disease and acute Asthma
2.5. Dicyclomine
2.5.1. Tablet
2.5.1.1. Used to treat intestinal hypermotility and symptom of irritable bowel syndrome
2.6. Oxybutynin
2.6.1. Tablet
2.6.1.1. Used relieve urinary and bladder difficulties
2.7. Benzhexol(Artane)
2.7.1. Tablet
2.7.1.1. Used of Cure disease parkinson