Thesis

1. 1er année: Accounting for pathways or grouped biomarkers in the development of high-dimensional prognostic survival models

1.1. Methods

1.1.1. Adaptive Lasso

1.1.1.1. MeanCoef

1.1.1.2. MaxWald

1.1.1.3. PCA

1.1.1.4. Lasso+PCA

1.1.1.5. Percentile.9

1.1.1.6. Representative

1.1.1.7. Predictor

1.1.2. IPF-Lasso

1.1.2.1. pflist1

1.1.2.2. pflist2

1.1.3. SGL

1.1.3.1. Default settings alpha = 0.95

1.2. Simulation

1.2.1. settings

1.2.2. Evaluation criteria

1.2.2.1. FDR

1.2.2.2. FNR

1.2.2.3. C-index

1.3. Application

1.3.1. Genomic data of breast cancer is available for 614 patients treated by adjuvant chemotherapy and 109 standardized genes

1.4. Publication

1.4.1. Statistics in Medicine

1.4.2. Statistical Methods in Medical Research (SMMR)

1.5. Seminaire

1.5.1. Poster

1.5.1.1. IBC: XXIXTH INTERNATIONAL BIOMETRIC CONFERENCE

1.5.2. Oral

1.5.2.1. Journée des Jeunes Chercheurs, LA SOCIÉTÉ FRANÇAISE DE BIOMÉTRIE

2. 2eme année

2.1. Methodes

2.2. Simulation

2.3. Application

2.4. Publication

2.4.1. Journal

2.5. Seminaire

3. 3eme année

3.1. Methodes

3.2. Simulation

3.3. Application

3.4. Publication

3.4.1. Journal

3.5. Seminaire