ANTIPSYCHOTIC DRUG

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ANTIPSYCHOTIC DRUG by Mind Map: ANTIPSYCHOTIC DRUG

1. TYPICAL

1.1. Example

1.1.1. Chlorpromazine

1.1.2. Haloperidol

1.1.3. Perphenazine

1.2. MOA

1.2.1. D2 antagonist

1.3. Side effect

1.3.1. Cognitive toxicity

1.3.2. Extrapyramidal symptoms

1.3.3. Sedation

2. ATYPICAL

2.1. Example

2.1.1. Clozapine

2.1.2. Olanzapine

2.1.3. Quetiapine

2.2. MOA

2.2.1. Serotonin 2A/D2 dopamine antagonism

2.3. Side effect

2.3.1. Sedation

2.3.2. Weight gain

2.3.3. Diabetes Mellitus

3. acts on

3.1. Mesolimbic

3.1.1. Regulate positive symptoms of psychosis

3.2. Mesocorticol

3.2.1. Involve in the negative and cognitive symptoms of Schizophrenia

3.3. Nigrostriatal

3.3.1. Regulate extrapyramidal nervous system and movement

3.4. Tuberoinfundibular

3.4.1. Regulate prolactin secretion