Genetics Week 3

1. Get Ready for Genetics and Genomics

1.1. The Process of Science

1.1.1. How Science Works

1.1.2. Science Literacy

1.2. Fundamentals

1.2.1. Life

1.2.2. Cells

1.2.3. Chemistry

1.2.4. Math and Statistics

1.2.5. Graphing

2. Basic Principles: How Genes Are Transmitted

2.1. Basic Genetics

2.1.1. Traits

2.1.2. DNA and Genes

2.1.3. Proteins

2.1.4. Chromosomes

2.1.5. Inheritance

2.1.6. Mutation

2.2. Mendel's Principles of Heredity

2.2.1. The Puzzle of Inheritance

2.2.2. Genetic Analysis According to Mendel

2.2.3. Mendelian Inheritance in Humans

2.3. Extensions to Mendel's Laws

2.3.1. Extensions to Mendel for Single-Gene Inheritance

2.3.2. Extensions to Mendel for Two-Gene Inheritance

2.3.3. Extensions to Mendel for Complex Trait Inheritance

2.4. Genes and Disease Part I

2.5. Chromosomes and Inheritance

2.5.1. Chromosomes: The Carrier of Genes

2.5.2. Mitosis: Cell Division that Preserves Chromosome Number

2.5.3. Meiosis: Cell Division that Halves Chromosome Number

2.6. Sex Chromosomes

2.6.1. Sex Chromosomes and Sex Determination

2.6.2. Gametogenesis

2.6.3. Sex Linkage

2.6.4. Sex-Linked and Sexually Dimorphic Traits in Humans

2.6.5. Human Intersexuality

2.7. Linkage, Recombination, and Gene Mapping

2.7.1. Gene Linkage and Recombination

2.7.2. Recombination: A Result of Crossing-Over During Meiosis

2.7.3. Mapping: Locating Genes Along a Chromosome

2.7.4. The Chi-Square Test and Linkage Analysis

2.7.5. Tetrad Analysis in Fungi

2.7.6. Mitotic Recombination and Genetics Mosaics

2.8. Genes and Disease Part II

3. What Genes Are and What They Do

3.1. Contemporary Uses of Genetics I

3.2. DNA Structure, Replication, and Recombination

3.3. Mutation

3.4. Using Mutations to Study Genes

3.5. Gene Expression: The Flow of Information from DNA to RNA to Protein

4. How Genes Travel on Chromosomes

4.1. The Eukaryotic Chromosome

4.2. Chromosomal Rearrangements

4.3. Ploidy

4.4. Bacterial Genetics

4.5. Organellar Inheritance

5. How Genes are Regulated

5.1. Gene Regulation in Prokaryotes

5.2. Gene Regulation in Eukaryotes

5.3. Epigenetics

6. Using Genetics

6.1. Manipulating the Genomes of Eukaryotes

6.2. Genetic Analysis of Development

6.3. Genetics of Cancer

7. Beyond the Individual Gene and Genome

7.1. Variation and Selection in Populations

7.2. Genetic Analysis of Complex Traits