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Unit 3: Genetics により Mind Map: Unit 3: Genetics

1. Chapter 4 (Alleles & Genes)

1.1. Mutational Effects on Alleles

1.1.1. Gain-of-function

1.1.2. Loss-of-function

1.1.3. Null Mutations

1.2. Types of Alleles

1.2.1. Wild vs. Mutant

1.2.2. Dominant & Recessive

1.3. Gene Interactions

1.3.1. Complete Dominance

1.3.2. Incomplete Dominance

1.3.3. Codominance

1.4. Molecular Basis of Allele Func.

1.4.1. Haplosufficiency

1.4.2. Haploinsufficiency

1.5. Lethal Alleles

1.6. Mult. Alleles & Allelic Series

1.6.1. Mulitple Alleles

1.6.2. Allelic Series

2. Chapter 2 (Cell Division)

2.1. Meisosis

2.1.1. Meiosis I

2.1.2. Meiosis II

2.1.3. Crossing Over

2.1.4. Independent Assortment

2.1.5. Haploid vs. Diploid

2.1.6. Gametes

2.2. Mitosis

2.2.1. Stages of Mitosis

2.2.1.1. Interphase

2.2.1.1.1. G1 phase

2.2.1.1.2. S phase

2.2.1.1.3. G2 phase

2.2.1.2. Prophase

2.2.1.3. Metaphase

2.2.1.4. Anaphase

2.2.1.5. Telophase

2.2.1.6. Cytokinesis

2.2.2. Sister Chromatids

3. Chapter 7 (Sex Determination & Linkage)

3.1. Traits influenced by sex

3.1.1. Sex-Limited Traits

3.1.2. Sex-Influenced Traits

3.2. Genetic Sex Determination

3.2.1. Ansiogamy

3.2.2. Male Heterogamety (XY/XX)

3.2.3. Female Heterogamety (ZW/ZZ)

3.2.4. Temp-Dependent Sex (TSD)

3.3. Dosage Comp. & X-Inactivation

3.3.1. Dosage Compensation

3.3.2. X-Inactivation

3.4. Sex Chromosome Anueplodies

3.4.1. Klinefelter Syndrome (47, XXY)

3.4.2. Turner Syndrome (45, X0)

3.4.3. Pseudoautosomal Regions (PARs)

3.5. Sex-Linked Inheritance Patterns

3.5.1. X-Linked Recessive

3.5.2. X-Linked Dominant

4. Chapter 3-4 (Inheritance Patterns & Pedigrees)

4.1. Modes of Inheritance

4.1.1. Autosomal Dominant

4.1.2. Autosomal Recessive

4.1.3. X-Linked Recessive

4.1.4. X-Linked Dominant

4.1.5. Y-Linked Inheritance

4.2. Pedigree Analysis

4.2.1. Symbols

4.2.1.1. Standard symbols

4.2.1.2. Roman numerals

4.2.2. Reading

4.2.3. Identifying carriers

4.3. Probability in Inheritance

4.3.1. Conditional Probability

4.3.2. Multiplication Rules

4.3.3. Pedigree-Based Risk Assessment

5. Chapter 3 (Mendelian Genetics)

5.1. Mendelian Genetics I

5.1.1. Punnett Square

5.1.2. Basic Probability

5.1.2.1. Monohybrid Crosss

5.1.2.1.1. Phenotypic Ratio

5.1.2.2. Dihybrid Cross

5.1.2.2.1. Phenotypic Ratio

5.1.3. Genotype vs. Phenotype

5.1.4. Test Cross

5.2. Key Mendelian Laws

5.2.1. Law of Segregation

5.2.2. Law of Inheritance

5.2.3. Law of Independent Assortment

5.2.4. Law of Dominance

5.3. Mendelian Genetics II

5.3.1. Trihybrid Crosses

5.3.1.1. 2^n formula

5.3.2. Advanced Probability

5.3.2.1. Conditional Probability

5.3.2.2. Product Rule

5.3.2.3. Sum Rules

5.3.2.4. Binomial Probability

5.3.2.4.1. Formula

5.3.3. Molecular Genetics of Mendel's

5.3.3.1. Loss-of-Function Mutations