Iatrogenic Causes to Pathological Conditions

1. Local Factors Causing Endodontic Failure in Pediatric Dentistry

1.1. Over instrumentation into periapical region

1.1.1. Pathological root resorption and early tooth loss

1.2. Incomplete infected tissue removal

1.2.1. Internal Root Resorption

1.3. Chemical Irritants

1.3.1. Using NaOCl instead of Chlorohexidine

1.4. Iatrogenic Errors

1.4.1. Midroot perforation

1.4.1.1. Early loss of tooth/ Abscess Formation

2. Faulty Administration of Local Anesthesia in Pediatric Dentistry

2.1. Neurologic – paresthesia

2.2. Infection – superficial or deep tissue/abscess

2.3. Local anesthetic systemic toxicity – mild (subjective symptoms, transient electrocardiogram changes) or severe (cardiac arrest or seizure)

3. Drug-related extrinsic tooth discolouration

3.1. Antibitotics

3.1.1. Tetracyclin

3.1.2. Ciprofloxacin

4. Drug-related osteonecrosis

4.1. Bisphosphonates

5. Drugs used in pregnancy that may induce cleft palate

5.1. Anticonvulsants

5.1.1. topiramate

5.2. Fluconazole

6. Radiotherapy

6.1. Pain, mucositis, hyposalivation, candidosis, caries, sialadenitis, osteoradionecrosis, fibrosis