Immune System

1. Gut

1.1. Gut bacteria

1.1.1. Vaginal birth vs caesarean section (bacterial coloniser-immune system link)

2. Autoimmune

2.1. autoimmune encephalitis

2.1.1. PANS/PANDAS

2.1.1.1. basal ganglia

2.1.1.1.1. anti-lysoganglioside antibodies

2.1.1.1.2. anti-tubulin antibodies

2.1.1.1.3. anti-dopamine D1 and D2 receptor antibodies

2.1.1.1.4. alterations to the enzyme tyrosine hydroxylase, resulting in increased synthesis of dopamine

2.1.1.1.5. dopaminergic and glutamatergic transmission and regulation are affected due to an increase in receptor sensitivity caused by antibody stimulation

3. MAIN MAP