Pharmacogenomics of drugs used to treat Covid-19- Group2

1. Types of drugs for treating Covid-19

2. Metabolic enzymes in metabolism of drugs used to treat Covid-19

3. remdesivir

4. angiotensin converting enzyme 2 (ACD2)

5. elevated aminotransferase and bilirubin levels

6. diarrhea, rash, renal impairment

7. hypotension

8. genomewide association study

9. cross-replicating association study

10. potential adverse events due pharmacogenetics variants or drug-drug interactions

11. Genetic risk factor could increase the risk of suffering severe Covid-19

12. GWAS studies

13. SARS-CoV-2

14. SARS-CoV

15. chloroquine and hydroxychloroquine diminish the effect of Remdesivir

15.1. CYP3A4 Inducers decrease the serum concentration of Remdesivir

16. MERS-CoV