Antiarrhythmics; Class II; BBs

1. MOA: blocks beta receptors and in nodal tissues (SA and AV)->interferes w/ ca entry; decrease conduction velocity, prolongs refractory period of the AV node

2. bisoprolol, metroprolol, carvedilol

3. uses

3.1. for atrial tachycardias, effects AV node

3.2. preferred for rate ctrl in afib

3.3. vent arrhythmias esp cxd by long QT

3.4. reduces mortality in post MI pts

4. AE

4.1. decreases HR, contractility

4.2. AV blocking

4.3. impotence

4.4. depression

4.5. cold extremities