Peripheral neuropathy

1. Def.

1.1. Degeneration/inflammation of P.N/Cr.N. with sensory,motor,autonomic manifestations.

2. Classification

2.1. Pathological

2.1.1. 1.neuronological

2.1.1.1. Cell body affection

2.1.1.1.1. e.g. paramalignant $

2.1.2. 2.demyelinating neuropathy

2.1.2.1. Myelin sheath degeneration

2.1.2.1.1. Due to immunological/infectious insult

2.1.3. 3.axonal neuropathy

2.1.3.1. Distal end of long axons degeneration

2.1.3.1.1. e.g. DM

2.2. Clinical

2.2.1. Mononeuropathy

2.2.1.1. Affection of single nerve trunk in one limb. e.g. ulnar /median N.

2.2.1.1.1. *Causes _trauma _DM _entrapment...carpal tunnel$. _Infection...HZS

2.2.2. Mono-neuropathy multiplex

2.2.2.1. >one trunk in one limb e.g. median &ulnar N

2.2.2.1.1. *causes _DM _pAN _leprosy _sarcoidosis

2.2.3. Polyneuropathy

2.2.3.1. Systemic affection of all PNs in all limbs

2.2.3.1.1. *causes

2.2.3.1.2. Clinical picture

2.2.3.1.3. Specific types

3. New Topic