Parkinson's Disease

1. Factors to consider when adjusting (link this to therapy is not effective, therapy is not safe and non-compliant above)

1.1. Untolerable side effects

1.2. No initial response

1.3. Sub-optimal response

1.4. Delayed onset

1.5. Wearing off

1.6. Freezing

1.7. Dyskinesias

1.7.1. Dystonias

2. Is treatment indicated?

2.1. To improve motor control and/or to improve non-motor symptoms

2.1.1. Yes

2.1.1.1. Patient-specific factors

2.1.1.1.1. Age

2.1.1.1.2. Comobidities

2.1.1.1.3. Other medications

2.1.1.2. Drug-specific factors

2.1.1.2.1. Side effect profile

2.1.1.2.2. Drug interactions

2.2. Drug-induced PD, Patient/Family unwilling to begin treatment and/or for solely neuroprotection

2.2.1. No

2.2.1.1. Provide non-pharm recommendations

2.2.1.2. Discontinue offending agent if drug-induced

3. Currently being treated

3.1. Therapy is effective

3.1.1. Therapy is safe

3.1.1.1. No compliance issues

3.1.1.1.1. Continue treatment as is

3.1.1.2. Non-compliant

3.1.2. Therapy is not safe (i.e untolerable side effects)

3.2. Therapy is not effective