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Interpersonal Context by Mind Map: Interpersonal Context

1. Social Context

2. Interpersonal Trauma


4. Systems for Social Processes (RDoC domain)

4.1. Affiliation and Attachment

4.1.1. Molecules 3CRF CRFR2 D1 Dopamine KOR Mu Opioid receptor Oxytocin Oxytocin Receptor Vasopressin Vasopressin 1a receptor

4.1.2. Cells Magnocellular OT

4.1.3. Circuits Amygdala BNST FF gyrus NAcc OFC PVN vmPFC VTA-NAcc-VP-Amygdala

4.1.4. Physiology Activation of sympathetic activity HPA-axis activation/Down regulation Immune Markers Immune responses Sex steroid changes Vagal Tone Vagal withdrawal

4.1.5. Behavior Attachment Formation - Maintaining Proximity Attachment Formation - Preference for Individual Attachment Maintenance - Distress upon separation

4.2. Social Communication

4.2.1. Reception of Facial Communication Molecules Dopamine FMRP GABA Oxytocin Serotonin Testosterone Vasopressin Cells Face Selective Neurons Mirror Neurons Circuits amygdala-brainstem IFG-INS-amygdala/VS OFC-ACC-amygdala-striatum Resting State Networks V1-FFA-STS-amygdala V1-FFA-STS-VS bilateral amygdalae and left inferior occipital cortex in ASD Physiology ECoG frontal brain asymmetry Facial EMG HR/BP/respiration Local cerebral blood flow changes N170 N250 Network Dynamics Pupil Dilation SCR Startle reflex Behavior Eye gaze detection identification of emotion implicit mimicry scanning patterns

4.2.2. Production of Facial Communication Molecules AP Contactin Circuits Eye movements (PPC-SC-SNc-SEF-FEF-CB) Facial Expression (Regions including PAG, AC) Physiology Facial EMG HRV NIRS Photoplethysmography (skin color measure of capillary dilation; temp) pupil dilation SC Tear Production Behavior Eye gaze aversion/contact Facial Affect Production Head Turning Imitation of Facial gestures Joint attention Reciprocal emotional expression Reciprocal eye contact

4.2.3. Reception of Non-Facial Communication Molecules Oxytocin Vasopressin circuits A1-RSTG (to be completed from

4.2.4. Production of Non-Facial Communication to be completed from

4.3. Perception and Understanding of Self

4.3.1. Agency to be completed from

4.3.2. Self-knowledge to be completed from

4.4. Perception and Understanding of Others

4.4.1. Animacy Perception to be completed from

4.4.2. Action Perception to be completed from

4.4.3. Understanding Mental States to be completed from