1. Type of sample
1.1. Randomized controlled trials.
1.1.1. Maqbali, 2013
1.1.2. Liu et al., 2016
1.1.3. Murkin, 2009
1.1.4. Mimoz et al., 2015
1.2. No geographical location mentioned.
1.2.1. Maqbali, 2013
1.3. Adults only.
1.3.1. Dorman & Dainton, 2011
1.3.2. Mimoz et al., 2015
1.4. Randomized trials
1.4.1. Mimoz et al., 2007
2. Data analysis
2.1. Randomization generated by computer.
2.1.1. Mimoz et al., 2015
2.1.2. Mimoz et al., 2007
2.2. Quantitative culture.
2.2.1. Murkin, 2009
2.3. Detsky scale
2.3.1. Liu et al., 2016
2.4. WinBUGS 1.43
2.4.1. Liu et al., 2016
2.5. STATA 13.0
2.5.1. Liu et al., 2016
2.6. Active control, open label.
2.6.1. Dorman & Dainton, 2011
2.7. Large quasi-experimental study
2.7.1. Maqbali, 2013
2.8. Cochrane collaboration protocol
2.8.1. Maqbali, 2013
2.9. Jadad score
2.9.1. Maqbali, 2013
3. Gaps
3.1. Perform trial with larger sample size/more case studies.
3.1.1. Maqbali, 2013
3.1.2. Dorman & Dainton, 2011
3.1.3. Liu et al., 2016
3.1.4. Murkin, 2009
3.1.5. Mimoz et al., 2007
3.2. Adherence to study not regularly audited.
3.2.1. Mimoz et al., 2015
3.3. Article included authors opinions.
3.3.1. Murkin, 2009
4. Level of evidence
4.1. Level 1
4.1.1. Liu et al., 2016
4.2. Level 2
4.2.1. Mimoz et al., 2007
4.2.2. Mimoz et al., 2015
4.3. Level 5
4.3.1. Dorman & Dainton, 2011
4.3.2. Maqbali, 2013
4.4. Level 6
4.4.1. Murkin, 2009
5. Purpose
5.1. To find to best antiseptic to reduce infections.
5.1.1. Maqbali, 2013
5.1.2. Dorman & Dainton, 2011
5.1.3. Liu et al., 2016
5.1.4. Murkin, 2009
5.1.5. Mimoz et al., 2007
5.1.6. Mimoz et al., 2015
6. Design
6.1. Randomly assigned
6.1.1. MImoz et al., 2007
6.1.2. Mimoz et al., 2015
6.2. Mixed methods
6.2.1. Maqbali, 2013
6.2.2. Dorman & Dainton, 2011
6.2.3. Liu et al., 2016
6.2.4. Murkin, 2009
7. Data collection
7.1. Randomized control trials
7.1.1. Maqbali, 2013
7.1.2. Dorman & Dainton, 2011
7.1.3. Liu et al., 2016
7.1.4. Murkin, 2009
7.1.5. Mimoz et al., 2007
7.1.6. Mimoz et al., 2015
8. Results
8.1. Support using chlorhexidine-alcohol over povidoine iodine-alcohol to prevent infection.
8.1.1. Maqbali, 2013
8.1.2. Dorman & Dainton, 2011
8.1.3. Murkin, 2009
8.1.4. Mimoz et al., 2007
8.1.5. Mimoz et al., 2015
8.2. No significance noted between antiseptics.
8.2.1. Liu et al., 2016
9. Limitations
9.1. Unable to do blind study due to color of solutions used.
9.1.1. Mimoz et al., 2007
9.1.2. Mimoz et al., 2015
9.2. Did not obtain ethical approval.
9.2.1. Maqbali, 2013
9.3. Research performed at just one location.
9.3.1. Dorman & Dainton, 2011
9.4. Data extracted by only 2 authors independently.
9.4.1. Lui et al. 2016
9.5. Did not clarify how to determine an invasive procedure.
9.5.1. Murkin, 2009