You speak English. Do you speak English? You do not speak English.
You will help him later. Will you help him later? You will not help him later.
You called Debbie. Did you call Debbie? You did not call Debbie.
You were studying when she called. Were you studying when she called? You were not studying when she called.
You are watching TV. Are you watching TV? You are not watching TV.
You have seen that movie many times. Have you seen that movie many times? You have not seen that movie many times.