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Pharmacology by Mind Map: Pharmacology

1. PAIN

1.1. Hydrocodone with acetaminophen

1.1.1. Decreased respirations might occur

1.2. Ergotamine sublingual

1.2.1. to treat migraine headaches

1.2.2. Teaching

1.2.2.1. Take one tablet at onset of migraine

1.2.3. AE

1.2.3.1. muscle pain

1.2.3.2. paresthesia​ in fingers and toes

1.2.3.3. cold, pale extremities

1.3. Morphine

1.3.1. via patient-controlled analgesia

1.3.1.1. assessment is the nurse's priority?

1.3.1.1.1. Respiratory rate

1.3.2. morphine sulfate PRN

1.3.2.1. AE

1.3.2.1.1. Urinary retention

1.3.3. Report

1.3.3.1. Pupillary constriction

1.4. Indomethacin

1.4.1. Nonsteroidal anti-inflammatory drug

1.5. Hydromorphone

1.5.1. Withhold if:

1.5.1.1. Bowel sounds are absent in all four quadrants.

1.5.2. complications include:

1.5.2.1. Constipation

1.5.2.1.1. increases the client’s ​risk for constipation

1.5.2.2. respiratory depression

1.5.2.3. orthostatic hypotension

1.5.2.4. urinary retention

1.6. Phenazopyridine

1.6.1. Common brands:

1.6.1.1. Urinary Pain Relief, Pyridium, Azo Urinary Pain Relief

1.6.2. outcomes of the medication

1.6.2.1. relieved burning upon urination

1.6.2.1.1. Relieves manifestations of burning with urination, pain, frequency, and urgency

1.7. Nitroglycerin

1.7.1. Nitroglycerin transdermal patches

1.7.1.1. understanding of the teaching

1.7.1.1.1. I will take the patch off right after my evening meal

1.7.2. Sublingual ​nitroglycerin​

1.7.2.1. Discard any tablets you do not use every 6 months

1.7.2.2. Sequence

1.7.2.2.1. Stop activity

1.7.2.2.2. Place tab under tongue

1.7.2.2.3. wait 5 min

1.7.2.2.4. call 911 if pain not relieved

1.8. Azathioprine

1.8.1. diagnostic tests prior to starting the medication?

1.8.1.1. Pregnancy test

1.9. Fentanyl lozenges

1.9.1. EDU

1.9.1.1. instruct the client to place the fentanyl stick between their cheek and lower gum and actively suck it for increased absorption of the medication.

1.9.1.2. periodically move the medication stick to a different location in the mouth for best absorption.

1.9.1.3. expect the medication's analgesia effects to begin within 10 to 15 min.

1.9.1.4. store unused, used, or partially used medication sticks in the safe storage container that comes in the kit when the medication is initially prescribed.

2. DIABETES

2.1. Administration

2.1.1. Factors that might cause the client to have difficulty safely self-administering insulin?

2.1.1.1. macular degeneration

2.1.2. New prescription for combination of lispro insulin and NPH Insulin.

2.1.2.1. I will mix these medications in one syringe

2.2. Insulin glargine

2.2.1. LONG-ACTING, manmade version of human insulin.

2.2.2. EDU

2.2.2.1. Observe for hypoglycemia when the insulin peaks

2.2.3. Insulin glulisine has a very short onset of action of 15 min.

2.3. DESMOPRESSIN

2.3.1. EDU

2.3.1.1. You can expect to have less urine output when you are taking this medication

2.4. Pioglitazone

2.4.1. AE

2.4.1.1. Fluid retention

2.4.1.1.1. also hepatoxicity, and increased LDLs

2.5. glipizide

2.5.1. adherence is effective when HbA1C is < 7%

2.6. Regular inuslin 10 units and NPH 30 units SQ 0730. Onset:

2.6.1. 0800

2.7. Metformin

2.7.1. manifestations of lactic acidosis, which rarely occur while taking metformin:

2.7.1.1. Myalgia

2.7.1.2. Malaise

2.7.1.3. Somnolence

2.7.1.4. hyperventilation

3. COLORS

3.1. Ranitidine

3.1.1. report yellowing of the skin

3.2. Isoniazid

3.2.1. Yellow skin tones

3.3. Digoxin

3.3.1. Yellow- tinged vision

3.4. Rifampin

3.4.1. urine and sweat can develop a red orange tinge

4. LUNGS/AIRWAY

4.1. fluticasone inhaler

4.1.1. spacer decreases the risk for:

4.1.1.1. Oral candidiasis

4.1.2. candidiasis

4.2. Albuterol

4.2.1. use during an acute asthma attack

4.2.2. The client should use the bronchodilator, albuterol, prior to taking beclomethasone, a glucocorticoid inhaler, to enhance its absorption.

4.2.3. albuterol D/C teaching with MDI for asthma. Recognize as priority assessment?

4.2.3.1. Fine motor control

4.3. Salmeterol

4.3.1. Bronchodilator

4.3.2. It can prevent asthma attacks and exercise-induced bronchospasm. It can also treat COPD, including chronic bronchitis and emphysema

4.3.3. Effectiveness of the medication

4.3.3.1. Improved breathing

4.4. Theophylline

4.4.1. EDU

4.4.1.1. “I will need to have blood levels drawn”

4.5. Montelukast

4.5.1. Control Inflammation in the airways

4.6. beclomethasone

4.6.1. The client should rinse their mouth after using beclomethasone, a glucocorticoid inhaler, to prevent oropharyngeal candidiasis and hoarseness.

4.7. Theophylline (Theo-Dur)

4.7.1. For chronic relief bronchitis

4.7.2. what indicates toxicity

4.7.2.1. Tremors

4.7.2.1.1. earliest manifestation Tremors because CNS stimulation. Others: insomnia, confusion, irritability

4.8. EDU

4.8.1. Use prior to physical activity?

4.8.1.1. Cromolyn

4.8.1.1.1. "I will use my cromolyn nebulizer before using my albuterol inhaler."

4.8.2. Discharge teaching for long term oral glucocorticoid for asthma. Include in teaching plan:

4.8.2.1. schedule on alt days to decrease side effects

4.9. MDI's

4.9.1. Add a spacer to each MDI.

4.9.1.1. A spacer applied to an MDI can make up for lack of hand-lung coordination by increasing the amount of medication delivered to the lungs.

5. ANTIBIOTICS

5.1. cefazolin IV

5.1.1. client has anxiety, hypotension, and dyspnea

5.1.1.1. Administer Epinephrine

5.1.2. Gentamicin

5.1.2.1. can potentiate nephrotoxicity

5.2. ciprofloxacin

5.2.1. report any signs of tendon pain or swelling

5.3. Ceftazidime

5.3.1. can treat bacterial infections.

5.3.2. Priority lab finding for the nurse to report to the provider before administering the medication?

5.3.2.1. Creatinine 2.6 mg/dl

5.4. oral amoxicillin/clavulanate

5.4.1. If urticaria is reported

5.4.1.1. Request a change in the type of the antibiotic

5.5. Gentamicin

5.5.1. AE

5.5.1.1. Tinnitus

5.6. Trimethoprim / Sulfamethoxazole

5.6.1. AE

5.6.1.1. Vesicular, crusty rash

5.7. Tetracycline

5.7.1. Take the medication with food

5.7.2. EDU

5.7.2.1. I will avoid drinking milk when I take this medication

5.7.2.2. I won’t worry if I experience diarrhea while taking this medication

5.7.2.3. DON'T take antacids with digoxin or tetracycline

5.7.2.3.1. Calcium carbonate

5.8. Clindamycin

5.8.1. Report

5.8.1.1. Watery diarrhea

5.9. Metronidazole

5.9.1. Alcohol:

5.10. Doxycycline

5.10.1. avoided during pregnancy

5.10.1.1. Avoid. Very serious interactions can occur

5.11. Broad spectrum antibiotics

5.11.1. risk for developing

5.11.1.1. Suprainfection

5.12. Cefaclor

5.12.1. indication of an allergic reaction​​?

5.12.1.1. Pruritus

5.12.1.1.1. Allergic reaction includes

5.13. EDU

5.13.1. The nurse should identify that an antibiotic can be administered 30 min before or after the scheduled time to maintain therapeutic blood levels without requiring an incident report.

6. Cardiac

6.1. Metoprolol

6.1.1. interventions

6.1.1.1. Determine apical pulse prior to administering

6.1.2. EDU

6.1.2.1. Check your pulse rate daily

6.1.3. AE

6.1.3.1. HYPOglycemia

6.1.3.1.1. "I might have difficulty recognizing when my blood sugar is low."

6.1.3.2. Can cause weight gain due to fluid retention.

6.1.3.2.1. The client should be taught to report unexpected weight gain, edema, and cough while taking beta-adrenergic blockers.

6.2. Digoxin

6.2.1. Adverse effects

6.2.1.1. Yellow- tinged vision

6.2.2. Digoxin Toxicity

6.2.2.1. Anorexia

6.2.2.2. Nausea

6.2.2.2.1. Check apical pulse

6.2.2.3. Vomiting

6.2.2.4. visual disturbances

6.2.2.5. Dysrhythmias

6.2.2.6. Hypokalemia increases the risk for toxicity

6.2.3. early indication of medication toxicity?

6.2.3.1. Visual disturbances

6.2.4. EDU

6.2.4.1. Don't take antacids with digoxin or tetracycline

6.2.4.2. These medications can increase ventricular irritability and put the client at risk for ventricular fibrillation after the synchronized countershock of cardioversion.

6.2.5. Cardiac glycosides, such as digoxin, are withheld prior to cardioversion.

6.2.5.1. These medications can increase ventricular irritability and put the client at risk for ventricular fibrillation after the synchronized countershock of cardioversion.

6.3. ACE inhibitors

6.3.1. lisinopril

6.3.1.1. Adverse effects

6.3.1.1.1. Persistent cough

6.3.1.2. works by relaxing blood vessels so blood can flow more easily

6.3.1.3. It can treat high blood pressure and heart failure. It can also reduce the risk of death after a heart attack.

6.3.2. captopril

6.3.2.1. Teaching

6.3.2.1.1. I should tell my provider if I develop a sore throat

6.3.2.1.2. How should captopril be taken?

6.3.2.2. contraindicated

6.3.2.2.1. When taking naproxen and other NSAIDS

6.3.2.3. AE

6.3.2.3.1. Neutropenia evidenced by a sore throat.

6.3.2.4. SE

6.3.2.4.1. Dysuria

6.3.2.4.2. urinary frequency

6.3.2.4.3. changes in the normal amount of urine.

6.3.3. Enalapril

6.3.3.1. AE

6.3.3.1.1. Hyperkalemia

6.4. Calcium-channel blockers

6.4.1. Diltiazem

6.4.1.1. EDU

6.4.1.1.1. This medication will lower blood pressure and is contraindicated for a client who is hypotensive.

6.4.1.2. Contraindication

6.4.1.2.1. Diltiazem and other calcium channel blockers are contraindicated for use in certain conditions where bradycardia is present, such as second- or third-degree heart block.

6.4.1.3. Use

6.4.1.3.1. It is used to treat tachydysrhythmia, such as:

6.4.1.3.2. Diltiazem can be a treatment option for essential hypertension.

6.5. Atropine

6.5.1. used to treat the symptoms of low heart rate (bradycardia), reduce salivation and bronchial secretions before surgery or as an antidote for overdose of cholinergic drugs

6.5.1.1. myasthenia gravis and is in a cholinergic crisis

6.6. Atorvastatin

6.6.1. For hyperlipidemia

6.6.2. Which of the following lab values should the nurse monitor?

6.6.2.1. Creatinine kinase

6.6.3. indicates the treatment has been effective?

6.6.3.1. LDL 120 mg/dL

6.6.3.1.1. LDL < 130 is the norm

6.7. Beta blockers

6.7.1. Atenolol

6.7.1.1. Use

6.7.1.1.1. It can treat high blood pressure and chest pain (angina). It can also reduce the risk of death after a heart attack.

6.7.1.2. AE

6.7.1.2.1. hypotension

6.8. Niacin

6.8.1. Use

6.8.1.1. It can treat high cholesterol and triglyceride levels as well as niacin deficiency.

6.8.1.2. AE

6.8.1.2.1. Flushing of the skin

6.9. The nurse should advise the client that decongestants

6.9.1. can constrict blood vessels

6.10. Taking aspirin daily for the past year

6.10.1. report

6.10.1.1. Hyperventilation

6.10.1.2. tinnitus

6.11. Epoetin alfa

6.11.1. monitor BP

6.12. Nitroprusside

6.12.1. Titrate according to

6.12.1.1. Blood pressure

6.12.2. Used in hypertensive crisis

6.13. Amiodarone

6.13.1. For life-threatening ventricular ​dysrhythmia

6.14. Clonidine (catapres)

6.14.1. EDU

6.14.1.1. Clonidine can cause drowsiness, weakness, sedation, and other CNS effects.

6.14.1.1.1. Until the client’s response to the medication is known, the nurse should instruct the client to avoid driving or handling other potentially hazardous equipment

6.14.1.1.2. Change position slowly

6.15. Procainamide

6.15.1. Brand name: Pronestyl

6.15.2. AE

6.15.2.1. Hypotension

6.15.2.1.1. If BP drops more than 15mmHg.

6.16. Verapamil

6.16.1. verapamil has more than one action

6.17. Adenosine

6.17.1. Monitor

6.17.1.1. Dyspnea

6.17.1.1.1. can occur during administration of adenosine due to bronchoconstriction

6.17.1.2. Flushing of the face and a feeling of warmth

6.17.1.2.1. transient findings that occur during administration of adenosine

7. SUBSTANCE ABUSE

7.1. Bupropion

7.1.1. aid to quit smoking

7.1.2. adverse effects

7.1.2.1. Insomnia

7.2. Diazepam

7.2.1. acute cocaine toxicity​

7.3. Heroin Overdose

7.3.1. A greatly decreased respiratory rate (8/min)

7.3.2. Pinpoint pupils

7.4. Chlordiazepoxide

7.4.1. First-line medication to use for a client who is experiencing manifestations of acute alcohol withdrawal

7.4.1.1. Prevent delirium tremens

8. Laxatives & Stool Softeners

8.1. Docusate sodium

8.1.1. Mechanism of action

8.1.1.1. reduces the surface tension of the stools to change their consistency

9. DIURETICS

9.1. Furosemide

9.1.1. Teaching

9.1.1.1. increase intake

9.1.1.2. Monitor for muscle

9.1.1.3. Dangle your legs

9.1.2. AE

9.1.2.1. dizziness

9.1.2.2. hypokalemia

9.1.2.2.1. The nurse should identify the presence of U-waves as a manifestation of hypokalemia, an adverse effect of furosemide.

9.1.2.2.2. EDU

9.1.2.3. urinary frequency

9.1.2.4. hypoglycemia

9.1.2.5. Dehydration

9.1.2.5.1. Oliguria, increased urine concentration, and an increase in urine specific gravity greater than 1.030 are expected findings in clients who are dehydrated.

9.1.3. desired therapeutic effect

9.1.3.1. A decrease in pulmonary or peripheral edema

9.1.3.2. weight loss

9.1.3.3. decrease BP

9.1.3.4. increase output

9.1.4. EDU

9.1.4.1. Loop diuretics, such as furosemide, can cause ototoxicity.

9.1.4.1.1. The client should be taught to notify the provider if tinnitus, a full feeling in the ears, or hearing loss occurs.

9.2. Mannitol

9.2.1. Use

9.2.1.1. used to force urine production in people with acute (sudden) kidney failure.

9.2.1.2. ICP

9.2.2. AE

9.2.2.1. Bibasilar crackles

9.2.2.2. Increased thirst

9.3. Acetazolamide

9.3.1. It can treat glaucoma, epilepsy, mountain sickness, and fluid retention (edema).

9.3.2. AE

9.3.2.1. Hypoglycemia

9.4. Bumetanide

9.4.1. same as FUROSEMIDE

9.4.2. EDU

9.4.2.1. You should monitor for hearing difficulties

9.4.2.1.1. complications include

9.5. Hydrochlorothiazide

9.5.1. AE

9.5.1.1. hypokalemia

9.5.1.1.1. Thiazide diuretics adverse effects

9.5.1.1.2. Eat foods rich in K

9.6. ​Triamterene​

9.6.1. (potassium sparring diuretic)

9.6.1.1. lab values should the nurse withhold the medication

9.6.1.1.1. Potassium 5.3

9.7. Client with dehydration secondary to diuretics.

9.7.1. Expect to find:

9.7.1.1. dry mucous membranes

9.8. Spironolactone

9.8.1. Potassium-sparing diuretic

9.8.1.1. Clients taking potassium-sparing diuretics should limit their intake of foods high in potassium due to the risk of hyperkalemia.

9.8.2. AE

9.8.2.1. Hyperkalemia

9.8.2.1.1. should NOT use salt substitutes because they contain potassium and place the client at risk for hyperkalemia.

9.8.2.2. Electrolyte imbalances, including hyponatremia, are common.

9.8.2.2.1. Drinking large amounts of water can cause dilutional hyponatremia, which is dangerous when taking spirolactone

9.8.3. EDU

9.8.3.1. Watch for increased breast tissue growth while taking this medication

9.8.3.2. Spironolactone, which is derived from steroids, can cause adverse endocrine effects, such as:

9.8.3.2.1. Gynecomastia

9.8.3.2.2. impotence in men

9.8.3.2.3. irregular menses, and hirsutism in women.

10. Anticoagulants ('blood thinners')

10.1. Warfarin

10.1.1. MOA

10.1.1.1. Used to treat or prevent venous thrombosis (swelling and blood clot in a vein) and pulmonary embolism (a blood clot in the lung).

10.1.1.2. Works by decreasing the clotting ability of the blood.

10.1.2. Administer if the client experiences bleeding

10.1.2.1. Vitamin K

10.1.3. Outside the expected range

10.1.3.1. INR 4.5

10.1.3.1.1. normal is 2-3 seconds

10.1.3.1.2. Warfarin check INR and PT (18-24 seconds)

10.1.4. EDU

10.1.4.1. Aspirin will increase the risk of bleeding

10.1.4.2. Interferes with the effectiveness of the oral contraceptives

10.1.4.3. Carry med alert bracelet at all times

10.1.5. Labs

10.1.5.1. Warfarin therapy is evaluated by PT and the INR, which is drawn daily for the first 5 days, then twice weekly for the next 1 to 2 weeks.

10.2. Heparin

10.2.1. heparin via continuous IV

10.2.1.1. discontinue when?

10.2.1.1.1. Platelet 96,000/mm3

10.2.1.2. fastest anticoagulation

10.2.2. Where to inject subcutaneous heparin?

10.2.2.1. abdomen in an area that is above the iliac crest and at least 5 cm (2 in) away from the umbilicus.

10.2.2.1.1. after injecting heparin subcutaneously?

10.2.3. manifestations of heparin toxicity?

10.2.3.1. Blood in urine

10.2.3.2. bruising

10.2.3.3. hematomas

10.2.3.4. hypotension

10.2.3.5. tachycardia

10.3. Enoxaparin (Lovenox)

10.3.1. EDU

10.3.1.1. Self Admin

10.3.1.1.1. Grasp the skin between the thumb and forefinger, while injecting the medication (SQ)

10.3.1.1.2. Alternate the injection sites between the side of the abdomen

10.3.1.1.3. Insert the entire length of the needle into the skin during injection

11. Bladder Relaxant

11.1. Oxybutynin

11.1.1. Used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination.

11.1.2. adverse effect

11.1.2.1. dry mouth

11.1.2.2. blurred vision

11.1.2.3. dry eyes

12. MENTAL HEALTH

12.1. Selective Serotonin Reuptake Inhibitor (SSRI)

12.1.1. Fluoxetine

12.1.1.1. AE

12.1.1.1.1. Muscle twitching

12.1.1.1.2. Sexual dysfunction

12.1.1.1.3. CNS

12.1.1.1.4. Agitation

12.1.1.1.5. euphoria

12.1.1.2. Teaching

12.1.1.2.1. I should take acetaminophen instead of ibuprofen for my headaches while taking this medication

12.1.2. Citalopram

12.1.2.1. Common brands: Celexa

12.1.2.2. AE

12.1.2.2.1. Confusion​

12.1.3. Paroxetine

12.1.3.1. AE

12.1.3.1.1. Drowsiness

12.2. Lithium

12.2.1. Used for mental illnesses, including bipolar disorder, depression, and schizophrenia.

12.2.2. discontinue

12.2.2.1. Ibuprofen

12.2.2.1.1. NSAIDs, such as naproxen and ibuprofen, increase renal reabsorption of sodium and lithium, which causes an increase in lithium levels and possible toxicity.

12.2.3. EDU

12.2.3.1. Vomiting or diarrhea can cause electrolyte imbalances.

12.2.3.1.1. Sodium

12.2.3.2. Diuretics

12.2.3.2.1. Diuretics decrease kidney excretion of lithium, which causes lithium levels to rise and increases the potential for toxicity.

12.3. Amitriptyline

12.3.1. AE

12.3.1.1. Dry mouth

12.3.2. EDU

12.3.2.1. Amitriptyline is Tricyclic and should be avoided especially during 1st trimester because associated with fetal abnormalities

12.4. Donepezil

12.4.1. Alzheimer's disease

12.4.2. AE

12.4.2.1. Dyspnea

12.5. Haloperidol

12.5.1. AE

12.5.1.1. Akathisia

12.6. Neuroleptic malignant syndrome (NMS)

12.6.1. A rare reaction to antipsychotic drugs

12.6.2. S/S

12.6.2.1. Fever

12.6.2.2. respiratory distress

12.6.2.3. diaphoresis

12.6.2.4. hyper and hypotension

12.6.2.5. incontinence

12.6.2.6. tachycardia

12.6.2.7. severe muscle rigidity

12.7. Clozapine

12.7.1. report to the provider immediately?

12.7.1.1. LDL 220 mg/dL ​

12.7.1.1.1. LDL should be < 130​

12.7.1.1.2. Monitor cholesterol triglycerides and blood glucose if weight gain is more than 14 kg (30 lbs.)

12.8. Lorazepam

12.8.1. Brand name: Ativan

12.8.2. Nurse Monitor

12.8.2.1. Sedation

12.8.2.1.1. Lorazepam is a benzodiazepine with anti-anxiety and sedative effects.

12.9. Buspirone

12.9.1. Delayed onset of action

12.10. Diazepam

12.10.1. Avoid alcohol

12.11. Phenelzine

12.11.1. Phenelzine, an MAOI, is an antidepressant.

12.11.2. This medication interacts with a variety of foods to produce a hypertensive crisis.

12.11.2.1. Beef steak and other meats that are fresh do not interact with phenelzine and are safe to consume.

13. TB

13.1. Isoniazid

13.1.1. adverse effect

13.1.1.1. Yellow skin tones

13.1.2. will need frequent monitoring of?

13.1.2.1. Aspartate aminotransferase (AST)

13.2. EDU

13.2.1. Client is prescribed a four-medications

13.2.1.1. “This regimen will eliminate various combinations of resistant strains of TB”

13.2.2. “You will need to take two or more medications to treat your disease”

13.3. Rifampin

13.3.1. urine and sweat can develop a red orange tinge

13.3.1.1. Document this as an expected finding

13.4. Mantoux skin test, for TB.

13.4.1. Appropriate nursing action:

13.4.1.1. insert with bevel up

13.4.1.2. 5-15 degree angle

13.4.1.3. 0.1mg or mL of stuff to form wheal

14. Cancer

14.1. Oprelvekin

14.1.1. Used to stimulate the bone marrow to produce platelets in order to prevent low platelets that may be caused by chemotherapy.

14.1.2. May be given to decrease the need for platelet transfusions

14.1.3. Indicate the effectiveness of the therapy?

14.1.3.1. Increased platelet count

14.2. Tamoxifen

14.2.1. AE

14.2.1.1. Hot flashes

14.2.2. for the treatment of breast cancer

14.3. Methotrexate

14.3.1. Chemotherapy and Immunosuppressive drug

14.3.2. It can treat cancer of the blood, bone, lung, breast, head, and neck. It can also treat rheumatoid arthritis and psoriasis.

14.3.3. Monitor and report:

14.3.3.1. Fever

14.3.4. Labs

14.3.4.1. BUN

14.3.4.1.1. Can cause kidney injury.

14.3.4.2. Platelets

14.3.4.2.1. Can cause thrombocytopenia.

14.3.4.3. HgB

14.3.4.3.1. Can cause bone marrow suppression.

14.3.4.4. AST

14.3.4.4.1. Can cause liver damage.

14.4. Filgrastim

14.4.1. nurse should monitor for an increase in which of the following types of cells to determine the effectiveness of the medication?

14.4.1.1. Granulocytes​

14.4.1.1.1. neutrophils, eosinophils, basophils, aka white blood cells.

14.4.1.1.2. Filgrastim stimulates the bone marrow to produce neutrophils. For clients receiving chemotherapy, the risk of infection is minimized.

14.4.2. Decreases the risk of infection in clients who have neutropenia from cancer.

14.4.2.1. Monitor CBC twice per week.

14.5. Fluorouracil

14.5.1. Antimetabolite antineoplastic agent

14.6. WHO analgesic ladder for cancer pain management

14.6.1. Oxycodone

14.6.1.1. An oral opioid that relieves moderate to moderately severe pain

15. ANTIDOTES

15.1. diazepam overdose

15.1.1. fluazenil

15.1.1.1. antidote used to reverse benzodiazepines

15.2. opioid overdose

15.2.1. heroin toxicity

15.2.1.1. naloxone

15.2.1.1.1. nurse should not administer naloxone too quickly

15.3. acute acetaminophen toxicity

15.3.1. Acetylcysteine

16. WOMEN'S HEALTH

16.1. Folic Acid

16.1.1. start taking before becoming pregnant

16.1.1.1. prevents neural tube defects

16.2. Betamethasone

16.2.1. The nurse understands the medication was effective when she observes which of the following?

16.2.1.1. The newborn has normal respiratory patterns

16.2.2. EDU

16.2.2.1. Patients taking beclomethasone should up their intake of what to minimize bone loss?

16.2.2.1.1. Vitamin D and calcium

16.2.3. Premature ROM in labor

16.3. Magnesium sulfate

16.3.1. Use

16.3.1.1. for preterm labor

16.3.2. Magnesium toxicity

16.3.2.1. Decreased level of consciousness

16.4. Tamoxifen

16.4.1. Estrogen modulator

16.4.2. It can treat breast cancer. It may also prevent breast cancer in women at high risk of developing it.

16.4.3. AE

16.4.3.1. Hot flashes

16.5. Ferrous sulfate

16.5.1. EDU

16.5.1.1. “Call your provider if you begin to bruise easily”

16.5.2. Used to treat and prevent iron deficiency anemia

16.6. Oxytocin (Pitocin)

16.6.1. nonreassuring FHR

16.6.1.1. Turn the client on the left side

16.6.2. Administration

16.6.2.1. administered via IV infusion when used for labor induction.

16.6.2.1.1. Effective uterine contractions should occur every 2 to 3 min.

16.6.2.1.2. The goal during oxytocin therapy is for the client to experience contractions that last from 45 to 60 seconds.

16.6.2.2. Can be administered IM to decrease postpartum bleeding.

16.7. Contraceptives

16.7.1. Carbamazepine

16.7.1.1. causes an accelerated inactivation of oral contraceptives because of its action on hepatic medication-metabolizing enzymes.

16.8. Nifedipine (adalat)

16.8.1. suppresses uterine contractions by doing what?

16.8.1.1. blocking calcium channels

17. GUT

17.1. Metoclopramide

17.1.1. Antiemetic and Gut motility stimulator

17.1.2. It can treat gastroesophageal reflux disease (GERD)

17.1.3. AE

17.1.3.1. Tardive dyskinesia

17.1.3.2. CNS effects

17.1.3.2.1. dizziness, fatigue, and sedation

17.1.4. Common brands

17.1.4.1. Reglan

17.2. Sucralfate

17.2.1. For PUD

17.2.2. Teaching

17.2.2.1. Forms a protective barrier over ulcers

17.3. Ranitidine

17.3.1. Use

17.3.1.1. Antihistamine and Antacid

17.3.1.1.1. It can treat and prevent heartburn

17.3.1.1.2. It can also treat stomach ulcers, GERD, and conditions that cause too much stomach acid.

17.3.2. EDU

17.3.2.1. It can be taken with or without food.

17.3.2.2. full course therapy is recommended.

17.3.2.3. Store at Room temperature

17.3.3. AE

17.3.3.1. Can be hepatotoxic and cause jaundice

17.4. Client who has peptic ulcer disease and is to start antacid therapy.

17.4.1. Take antacids 1 hour after meals, 3 hours after meals, and at bedtime

17.5. Bismuth Subsalicylate (Pepto)

17.5.1. Useful against H Pylori, and also coats stomach providing protection from gastric juices

17.6. alosetron

17.6.1. The client must sign an agreement with the provider before beginning alosetron.

17.6.2. EDU

17.6.2.1. notify the provider and stop the medication if diarrhea is not controlled after 1 month of starting alosetron.

17.6.2.2. notify the provider about tachydysrhythmia

17.7. omeprazole

17.7.1. EDU

17.7.1.1. should take omeprazole once daily before a meal (usually breakfast) because the medication is less effective when taken with food.

17.7.1.2. Should be used for no more than 1 to 2 months due to long-term adverse effects

17.7.2. Clients who have active duodenal ulcer or gastric reflux disease

18. NERVOUS SYSTEM

18.1. Methylprednisolone

18.1.1. Common brands:

18.1.1.1. Depo-Medrol, Medrol, Solu-Medrol

18.1.2. Teaching

18.1.2.1. Blood glucose

18.1.2.2. Avoid contact

18.1.2.3. Grapefruit juice

18.1.3. Steroid

18.1.3.1. It can treat inflammation, severe allergies, flares of chronic illnesses, and many other medical problems.

18.2. Phenytoin

18.2.1. EDU

18.2.1.1. “I should take my medication with milk to minimize gastric upset”

18.2.2. Anticonvulsant

18.2.2.1. It can treat and prevent seizures

18.2.3. Report

18.2.3.1. Cognitive impairment

18.3. Neostigmine

18.3.1. Muscle strengthener

18.3.2. It can treat myasthenia gravis

18.3.3. AE

18.3.3.1. Tachycardia

18.4. Valproic acid

18.4.1. Anticonvulsant

18.4.2. It can treat seizures and bipolar disorder. It can also help prevent migraine headaches

18.4.3. Monitor and report:

18.4.3.1. Muscle pain

18.5. Benzatropine

18.5.1. Anti-Tremor

18.5.2. It can treat Parkinson's disease and side effects of other drugs.

18.5.3. Monitor for

18.5.3.1. Tachycardia

18.6. Atarax Brand name: Vistaril

18.6.1. dry mouth

19. Gout

19.1. Allopurinol

19.1.1. Teaching

19.1.1.1. Drink 2 L of water a day

19.1.1.2. Take after meals

19.1.1.2.1. to minimize GI distress, insomnia, headache

19.1.1.2.2. Advise clients to take oral gout medication with food or after meals

20. MUSCLE RELAXERS

20.1. Dantrolene

20.1.1. Reconstitute the initial dose with 60 ml of sterile water without a bacteriostatic agent

20.2. Cyclobenzaprine

20.2.1. EDU

20.2.1.1. Taper off the medication before discontinuing it

20.3. Baclofen

20.3.1. therapeutic outcome

20.3.1.1. Decrease in paralysis of the extremities

20.4. Succinylcholine

20.4.1. AE

20.4.1.1. hyperthermia

20.4.1.1.1. Stop succinylcholine

20.4.1.1.2. Give oxygen

20.4.1.1.3. Give cooling measure

20.4.1.1.4. Ice to groin

20.4.1.1.5. Give dantrolene

21. OSTEOPOROSIS

21.1. risedronate

21.1.1. Teaching

21.1.1.1. I should sit up for 30 minutes after taking the risedronate

21.1.1.2. With a full glass of what in the mornings

21.1.1.3. When should the immediate release and delayed-release form of risedronate be taken related to food intake?

21.1.1.3.1. Immediate release: At least 30 min prior to eating

21.1.1.3.2. Delayed-release: Can be taken after eating.

21.1.1.4. When on risedronate, when should a patient take an antacid?

21.1.1.4.1. Absorption of risedronate is reduced in antacids containing calcium, aluminum, or magnesium.

21.1.1.4.2. The nurse should instruct the client to take the antacid 2 hours after taking risedronate.

21.1.2. contraindicated

21.1.2.1. When client cannot sit or stand upright for 30 minutes

21.1.3. AE

21.1.3.1. GI effects such as esophagitis and dyspepsia.

21.1.3.1.1. The client should sit up for 30 min after taking med

21.2. Calcitonin salmon

21.2.1. used to treat osteoporosis in women who are at least 5 years past menopause and cannot or do not want to take estrogen products.

21.2.2. long-term treatment therapy for postmenopausal osteoporosis

21.2.3. Intranasal spray

21.2.3.1. depress the side arms to activate the pump

21.2.3.1.1. Instruct the client to activate the pump on the initial use by holding the bottle upright and depressing the two white side arms toward the bottle six times.

21.2.3.2. administer calcitonin-salmon to one nostril daily, alternating nostrils.

21.2.3.3. nasal bleeding, or ulcerations, are indications to discontinue the medication and to notify the provider if nasal bleeding occurs.

22. Antithyroid agent

22.1. Propylthiouracil

22.1.1. A thyroid hormone antagonist that decreases the circulating T4 hormone

22.1.1.1. reducing the manifestations of hyperthyroidism.

22.1.1.2. medication has been effective?

22.1.1.2.1. Increase in ability to focus

22.1.1.2.2. More sleep

22.1.1.2.3. Decrease or normal appetite

22.1.2. AE

22.1.2.1. decreased WBC count

22.2. Levothyroxine

22.2.1. After 6 weeks of treatment, the nurse determines that the medication was effective if the

22.2.1.1. thyroid-stimulating hormone (TSH) level is 2 microunits/mL

22.2.2. What indicates the need for an ​increase in dosage​?

22.2.2.1. Cold intolerance

22.2.3. AE

22.2.3.1. Acute levothyroxine overdose

22.2.3.1.1. Tachycardia

22.2.3.1.2. Heat intolerance

22.2.3.1.3. Hyperthermia

22.2.3.1.4. Tremor and anxiety

22.2.4. EDU

22.2.4.1. The nurse should instruct the client to avoid taking calcium within 4 hr of levothyroxine administration.

22.3. Methimazole

22.3.1. Increased sleeping

23. CONTRACEPTIVES

23.1. Interferes with the effectiveness of the oral contraceptives

23.1.1. Warfarin

24. STEROIDS

24.1. Prednisone

24.1.1. Expect to undergo which of the following diagnostic test to monitor long-term complications?

24.1.1.1. Electrocardiograms

24.2. Dexamethasone

24.2.1. Brand name: Decadron

24.2.1.1. More susceptible to developing infection

25. ANTIFUNGAL

25.1. Amphotericin B

25.1.1. AE

25.1.1.1. Bradycardia

25.1.2. Infusion reaction includes:

25.1.2.1. Fever

25.1.2.2. Chills

25.1.2.3. Rigors

25.1.2.4. headache 1-3 hrs. after initiation

26. ANEMIA

26.1. cyanocobalamin

26.1.1. vitamin B12

26.1.1.1. helps convert folic acid to active form​)

26.1.2. EDU

26.1.2.1. Use a nasal decongestant 15 minutes before the medication if you have a stuffy nose

26.2. Ferrous gluconate (IRON)

26.2.1. Used to treat or prevent iron deficiency anemia

26.2.2. EDU

26.2.2.1. I should stay upright for at least 15 minutes after medication

26.3. INFeD (Iron Dextran Injection USP)

26.3.1. IM

26.3.1.1. What is an appropriate site?

26.3.1.1.1. Vastus Lateralis

27. HIV

27.1. efavirenz

27.1.1. Notify the provider for the appearance of a skin rash

27.2. Contraindication for varicella vaccination

28. RENAL

28.1. Cyclosporine (Sandimmune)

28.1.1. EDU

28.1.1.1. I will need to take it:

28.1.1.1.1. For the rest of my life

28.1.2. AE

28.1.2.1. HTN

28.1.2.1.1. Half the clients who take cyclosporine develop a 10% to 15% increase in blood pressure and might need to start antihypertensive therapy.

28.2. Epoetin alfa

28.2.1. AE

28.2.1.1. HTN

28.2.1.1.1. Causes HTN, which can lead to stroke or other cardiovascular complications.

29. LABS

29.1. Calcium

29.1.1. A calcium level of 9.2 mg/dL is within the expected reference range of 9.0 to 10.5 mg/dL

29.2. magnesium

29.2.1. A magnesium level of 1.6 mEq/L is within the expected reference range of 1.3 to 2.1 mEq/L

29.3. digoxin

29.3.1. A digoxin level of 1.1 ng/mL is within the expected reference range of 0.8 to 2 ng/mL

29.4. potassium

29.4.1. A potassium level of 2.8 mEq/L is below the expected reference range of 3.5 to 5 mEq/L

30. Herbal Supplements

30.1. saw palmetto

30.1.1. Promote urinary health.

30.1.2. r/t prostatic conditions like BPH